cells, replication, evolution, information, and energy
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theory
an explanation for a very general class of phenomena or observations and is supported by a wide body of evidence
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Scientific theory
is an explanation of some aspect of the natural world that has been substantiated through repeated experiments
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Three Theories
the cell theory, the theory of evolution by natural selection, and the chromosome theory of inheritance
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Robert Hooke and Anton van Leeuwenhoek
first to observe cells
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cell
a highly organized compartment bounded by a plasma membrane
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cell theory
idea that all living things are composed of cells, cells are the basic units of structure and function in living things, and new cells are produced from existing cells
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phylogeny
Evolutionary history of a species
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plasma membrane
A selectively-permeable phospholipid bilayer forming the boundary of the cells
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phospholipids
A molecule that is a constituent of the inner bilayer of biological membranes, having a polar, hydrophilic head and a nonpolar, hydrophobic tail.
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lipids
carbon containing compounds found in organisms, largely non polar and hydrophobic, fats are lipids
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hydrocarbons
Compounds composed of only carbon and hydrogen
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isoprenoid
hydrocarbon chain that functions as pigments, scents, vitamins
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fatty acid
a hydrocarbon chain bonded to a carboxyl functional group
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Saturated hydrocarbon chains
Consist of only single bonds between the carbons
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unsaturated hydrocarbon chains
have at least one double bond
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three most important types of lipids found in cells
steroids, fats, and phospholipids
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phospholipids
consist of a glycerol linked to a phosphate group bonded to a charge or polar molecule
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steroids
are a family of lipids distinguished by a bulky, four-ring structure
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hydrophobic interactions
become stronger as saturated hydrocarbon tails increase in length
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passive transport
occurs when substances diffuse across a membrane in the absence of an outside energy source
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osmosis
diffusion of water
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hypertonic
when comparing two solutions, the solution with the greater concentration of solutes
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hypotonic
Having a lower concentration of solute than another solution
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isotonic
when the concentration of two solutions is the same
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fluid-mosaic model
model that describes the arrangement and movement of the molecules that make up a cell membrane
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selective permeability
A property of a plasma membrane that allows some substances to cross more easily than others.
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ion channels
A transmembrane protein channel that allows a specific ion to diffuse across the membrane down its concentration or electrochemical gradient.
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channel proteins
proteins that provide passageways through the membrane for certain hydrophilic (water-soluble) substances such as polar and charged molecules
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aquaporins
water channel proteins
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gated channels
A protein channel in a cell membrane that opens or closes in response to a particular stimulus.
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facilitated diffusion
Movement of specific molecules across cell membranes through protein channels
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carrier proteins
a protein that transports substances across a cell membrane
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morphology
study of form
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eukaryotes
have a membrane-bound nucleus
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prokaryotes
lack a membrane bound nucleus
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bacterial cells
have a plasma membrane that consists of a phospholipid bilayer, has proteins that regulate what enters and exits the cell, and creates a distinct internal environment
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cytoplasm
A jellylike fluid inside the cell in which the organelles are suspended
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prokaryotic cells
contain a single, circular chromosome, composed of DNA and proteins, contain genes which code for polypeptides, tightly coiled to fit inside the cell
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plasmids
small circular DNA molecules that replicate separately from the bacterial chromosome
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nucleoid
A dense region of DNA in a prokaryotic cell.
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cytoskeleton
A network of fibers that holds the cell together, helps the cell to keep its shape, and aids in movement
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peptidoglycan
a structural polymer found in bacterial cell walls joined by beta-1-4 glycosidic linkages
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eukaryotic chromosomes
are found inside a membrane-bound compartment called a nucleus
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eukaryotic cells
are often much larger, feature a diverse and dynamic cytoskeleton, and contain extensive amounts of internal membrane
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eukaryotic cells
have large surface-to-volume ratio
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cytosol
Fluid portion of cytoplasm
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nuclear envelope
layer of two membranes that surrounds the nucleus of a cell
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nucelar lamina
lattice-like sheet of fibrous proteins
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Nucleolus
Makes ribosomes
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Heterochromatin
Eukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed.
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euchromatin
The less condensed form of eukaryotic chromatin that is available for transcription.
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Ribosomes
Makes proteins
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Rough Endoplasmic Reticulum
An endomembrane system covered with ribosomes where many proteins for transport are assembled.
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Smooth Endoplasmic Reticulum
creates lipids or fat and is a reservoir for calcium ions
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Golgi apparatus
stack of membranes in the cell that modifies, sorts, and packages proteins from the endoplasmic reticulum
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cisternae
flattened stacked membrane folds
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cis
surface closest to the nucleus
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trans
surface is oriented toward the plasma membrane
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lysosomes
recycling centers only found in animal cells
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endomembrane system
lysosomes, golgi apparatus, and ER
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vacuoles
Cell organelle found in plants and fungi that stores materials such as water, salts, proteins, and carbohydrates
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peroxisomes
Contain oxidase enzymes that detoxify alcohol, hydrogen peroxide, and other harmful chemicals
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Mitochondria
An organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur.
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cristae
folds in the inner membrane of mitochondria
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mitochondrial matric
the substance occupying the space enclosed by the inner membrane of a mitochondrion; it contains enzymes, filaments of DNA, granules, and inclusions of protein crystals, glycogen, and lipid.
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chloroplasts
Capture energy from sunlight and use it to produce food for the cell
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thylakoids
A flattened membrane sac inside the chloroplast, used to convert light energy to chemical energy.
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grana
stacks of thylakoids
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stroma
fluid portion of the chloroplast; outside of the thylakoids
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endosymbiosis
A theorized process in which early eukaryotic cells were formed from simpler prokaryotes.
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microfilaments
Long, thin fibers that function in the movement and support of the cell
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microtubules
Spiral strands of protein molecules that form a tubelike structure
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intermediate filaments
Threadlike proteins in the cell's cytoskeleton that are roughly twice as thick as microfilaments
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actin filaments (microfilaments)
small fibrils that forms a bundles, sheets or networks in the cytoplasm; for structure, support for microvilli, contractility and movement
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dimers
two monomers bonded together
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microtubule organizing center
any structure that organizes microtubules
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centrosome
A structure in animal cells containing centrioles from which the spindle fibers develop.
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centrioles
Cell organelle that aids in cell division in animal cells only
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nuclear localization signal (NLS)
A short amino acid sequence that marks a protein for delivery to the nucleus.
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extracellular matrix
The substance in which animal tissue cells are embedded, consisting of protein and polysaccharides.
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collagen
A glycoprotein in the extracellular matrix of animal cells that forms strong fibers, found extensively in connective tissue and bone; the most abundant protein in the animal kingdom.
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proteoglycans
a glycoprotein consisting of a small core protein with many carbohydrate chains attached, found in the extracellular matrix of animal cells.
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tissues
Groups of cells with a common structure and function.
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laminins
ECM crosslinking proteins
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integrins
membrane proteins; they transmit signals between the ECM and cytoskeleton
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primary cell wall
In plants, a relatively thin and flexible layer first secreted by a young cell.
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microfibrils
A threadlike component of the cell wall, composed of cellulose molecules
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pectin
a soluble gelatinous polysaccharide that is present in ripe fruits and is extracted for use as a setting agent in jams and jellies.
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multicellularity
The state of being composed of many cells that adhere to each other and do not all express the same genes with the result that some cells have specialized functions.
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epithelia
layers of cells that cover internal or external surfaces
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tight junction
A type of intercellular junction in animal cells that prevents the leakage of material between cells.
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desmosomes
Anchoring junctions that prevent cells from being pulled apart
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gap junctions
(communicating junctions) provide cytoplasmic channels between adjacent cells
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symplast
In plants, the continuum of cytoplasm connected by plasmodesmata between cells.
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apoplast
In plants, the continuum of cell walls plus the extracellular spaces.
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ketose
carbonyl group in middle of carbon chain
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aldose
carbonyl group at end of carbon chain
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endocrine signaling
Specialized cells release hormone molecules into vessels of the circulatory system, by which they travel to target cells in other parts of the body.
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surface proteins
A protein that resides primarily on the inner or outer surface of the phospholipid bilayer which constitutes the plasma membrane of the cell.