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Resting Zone
Inactive chondrocytes
Zone of Proliferation
Mitosis + columns formed
Zone of Maturation
Enlargement + rounder + spaced: cartilage matrix made
Zone of Hypertrophy
Enlargement + VEGF: cartilage matrix made
Zone of Degeneration
Chondrocytes degenerate + cartilage matrix calcifies + lacunae fuse to form marrow cavity: bone matrix made
Zone of Ossification
Osteoblasts line cartilage + osteoclast create bone