Immunohematology Deferrals, components, phlebotomy donors

Conditions for indefinite/ permanent deferrals

HEP B, HEP C, human T-cell lymphotropic virus, HIV, Babesiosis, Chagas disease, CJD, recipient of dura mater/ human pituitary growth hormone, use of needle with nonprescription drugs

Malaria (lived in endemic area) deferral period

(traveled to endemic area)

3 years

1 year

Prison greater than 72 hrs

1 year

Leishmaniasis (traveled to Iraq) deferral period

1 year

Finasteride (Proscar)

deferral:

1 month

Finasteride (Propecia)

deferral:

1 month

Isotretinoin (accutane)

deferral:

1 month

Acitretin (soriatane)

deferral:

3 years

Etretinate (Tegison)

deferral:

permanent/ indefinite

Warfarin (coumadin)

deferral:

1 week

Aspirin and piroxicam (Feldene)

deferral:

2 days after last dose for plt donors

Clopidogrel (Plavix)

deferral:

14 days for plt donors

HEP B immune globulin

deferral:

1 year

Reasons for 2 week deferral

Measles, Mumps, Polio, Typhoid, Yellow fever vaccine

Reasons for 4 week deferral

German measles, Varicella zoster vaccine

Reasons for 6 week deferral

pregnancy

Reasons for 12 week deferral

permanent tattoos, mucous membrane/ skin penetration exposure to blood, sexual contact with individual at high risk of HIV, incarceration, complete therapy for syphilis, transfusion of blood, human diploid cell rabies vaccine after animal bite

Hgb range (female/male)

F: 12.5 g/dl

M: 13 g/dl

Hgb range (autologous)

11 g/dl or higher

Hct ranges (female/male)

F: 38%

M: 39%

Hct ranges (autologous)

33% or higher

BP ranges

systolic: 90-180 mm

diastolic: 50-100 mm

Temperature range

< or greater to 37.5 C (99.5 F)

Pulse range

50-100 bpm

Weight range

minimum 110 lbs

Age range

at least 16 yrs of age

1. Whole blood

Storage/shipping temp:

storage: 1-6 degrees C

shipping: 1-10 degrees C

CPD,CP2D expiration

21 days

CPDA expiration

35 days

2. RBC’s

storage/ shipping temp:

storage: 1-6 degrees C

shipping: 1-10 degrees C

AS expiration

42 days

3. Frozen RBC’s

storage temp:

CPD,CPDA-1 exp:

less then -65 degrees C

10 years

3. RBC’s Deglycerolized/ washed (open system)

storage temp:

expiration:

1-6 degrees C

24 hours

4. Irradiated RBC’s

   storage temp:

   expiration:

1-6 degrees C

28 days from irradiation or original outdate

5. RBC’s leukocytes reduced

   storage temp:

   expiration:

1-6 degrees C

depends on anticoagulant/ preservative

6. Plasma, Frozen within 24 hours after phlebotomy (PF24)

   storage temp:

   expiration:

less than -18 degrees C

12 months

7. Fresh Frozen Plasma

storage temp:

expiration:

less than -18 degrees C/ less than -65 degrees C

12 months/ 7 years

8. FFP,PF24,Thawed

   storage temp:

   expiration:

1-6 degrees C

24 hours

9. Thawed plasma

   storage temp:

   expiration:

1-6 degrees C

5 days from thawing

10. Cryoprecipitated AHF

    storage temp:

    expiration:

less than -18 degrees C

12 months

11. Pooled cryoprecipitated AHF (after thawing)

    storage temp:

    expiration:

20-24 degrees C

4 hours

12. Platelets

    storage temp:

    expiration:

20-24 degrees C wash continuous agitation

5 days

13. Pooled platelets (open system)

    storage temp:

    expiration:

20-24 degrees C with continuous agitation

4 hours

14. Apheresis platelets Leukocytes reduced

    storage temp:

    expiration:

20-24 degrees C with continuous agitation

open system exp- 4 hours

closed system exp- 5 days

15. Apheresis Granulocytes

    storage temp:

    expiration:

20-24 degrees C

24 hours

Platelet paresis

3 X 10^11

Donor unit Ph concentrate

5.5 X 10^10