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Electrolytes
potassium, sodium, calcium, magnesium
Electrolyte responsibilities
balancing water, pH level, moving waste out of cells, moving nutrients into cells, allowing body to function properly
Fluid
water containing glucose, mineral salts, and proteins, extracellular and intracellular
Extracellular fluid
outside cells, ⅓ total body water, intravascular, interstitial, and transcellular
What fluid contains sodium, chloride, and bicarbonate?
extracellular fluid
Intravascular fluid
blood plasma
Interstitial fluid
between cells, outside of blood vessels
Transcellular fluid
CSF, pleural, peritoneal, synovial
Intracellular fluid
inside cells, ⅔ total body water, balanced via membrane permeability
What fluid contains potassium, magnesium, phosphates, and proteins?
intracellular fluid
Cellular effect of isotonic solution
cells normal shape, no loss or gain
Cellular effect of hypertonic solution
cells lose water and shrink
Cellular effect of hypotonic solution
cells swell, water rushes in
Clinical dehydration
extracellular volume deficit and hypernatremia at same time, usually caused by gastroenteritis
Fluid intake
drinking and eating, food metabolism, IV, rectal, irrigation of body cavities
Fluid distribution
movement of fluid, ECF vs ICF occurs by osmosis, vascular vs interstitial ECF occurs by filtration
Fluid output
skin, lungs, GI, kidneys, insensible losses via lungs and skin
Hormones affecting fluid balance
ADH, RAAS, ANP
Extracellular fluid volume deficit causes
decreased oral intake of water and salt, increased GI output, increased renal output, loss of blood or plasma, massive sweating without water and salt intake
Extracellular fluid volume deficit signs and symptoms
sudden weight loss, postural hypotension, tachy, thready pulse, poor skin turgor, flat neck veins, dark yellow urine, restless, confusion, oliguria, cold and clammy, increased HCT, increased BUN and specific gravity
Extracellular fluid volume deficit treatment
identify underlying cause, treat underlying cause, replace fluids
Extracellular fluid volume excess causes
excess isotonic IVF, oral intake of salty foods and water, renal retention of Na and water, heart failure, cirrhosis, aldosterone or glucocorticoid excess, acute or chronic oliguric renal disease
Extracellular fluid volume excess signs and symptoms
sudden weight gain, edema, full neck veins, crackles, confusion, pulmonary edema, decreased HCT, decreased BUN
Extracellular fluid volume excess treatment
diuretics, restricting sodium and fluids, sit patient up in bed
Untreated hypovolemia
cyanosis, change in LOC, chest pain, palpitations, no urine, tachypnea, tachycardia, decreased BP, weak pulse
Hypovolemic shock
body has lost 20 percent or ⅕ of blood/fluid supply, treatment aimed at controlling fluid/blood loss
What can lead to electrolyte imbalances
dehydration, overhydration, certain medications, heart, kidney, and liver disorders, incorrect IV fluids or feedings
Normal potassium values
3.5 to 5 mEq/L
Normal sodium values
135 to 145 mEq/L
Normal calcium values
9 to 11 mEq/L
Normal magnesium values
1.5 to 2.5 mEq/L
Hypernatremia causes
loss of more water than salt (diabetes insipidus, large insensible perspiration), gain of more salt than water (tube feedings, hypertonic IVF, lack of access to water, dysfunction of osmoreceptors)
Hypernatremia s and s
decreased LOC, thirst, seizures, high serum osmolality
Hypernatremia treatment
slow and careful D5W or hypotonic fluid administration, seizure precautions, neuro checks, avoid rapid reduction of sodium
Hyponatremia causes
gain of more water than salt (excessive ADH, excess water intake, excessive D5W, hypotonic irrigation, tap water enema), loss of more salt than water (replacing large body output with water but no salt
Hyponatremia s and s
decreased LOC, seizures, low serum osmolality
Hyponatremia treatment
increase or decrease oral intake depending on cause, correct sodium levels SLOWLY to prevent cardiac overload
Hypokalemia causes
decreased intake, shift of K into cells, increased K output (N/V, diuretics)
Hypokalemia s and s
muscle weakness, abdominal distension, decreased bowel sounds, constipation, dysrhythmia, U waves, flattened T waves, ST segment depression
Hypokalemia treatment
potassium diet, oral supplements, IV, watch s and s
Hyperkalemia causes
increased K intake, shift K out of cells, insufficient insulin, decreased K output, use of K sparing diuretics, adrenal insufficiency
Hyperkalemia s and s
bilateral muscle weakness in quadriceps, abd cramps, dysrhythmia, cardiac arrest, peaked T waves, widened QRS complex, PR prolongation, terminal sine wave pattern
Hyperkalemia treatment
sodium bicarb (acidosis), calcium gluconate (dysrhythmias), insulin, increase excretion, dialysis, medications, iv fluids
Hypocalcemia causes
decreased Ca intake and absorption, shift of Ca into bone, increased Ca output
Hypocalcemia s and s
numbness of fingers, toes, and mouth, chvosteks sign, hyperactive reflexes, muscle twitching, prolonged ST segments
Hypocalcemia treatment
oral or IV Ca, may need vitamin D
Hypercalcemia causes
increased Ca intake and absorption, shift of Ca out of bone, decreased Ca output
Hypercalcemia s and s
anorexia, N/V, fatigue, decreased LOC, cardiac arrest, heart block, shortened ST segments
Hypercalcemia treatment
rehydration, mobility, oral phosphate, calcitonin, corticosteroids, iv fluids and diuretics, biphosphonates
Hypomagnesemia causes
decreased mag intake and absorption, shift of mag into inactive form, increased mag output
Hypomagnesemia s and s
positive chvosteks sign, muscle cramps, twitching, seizures, tachycardia, HTN, prolonged QT interval
Hypomagnesemia treatment
magnesium supplements, 1g for mg/hour for iv infusion
Hypermagnesemia causes
increased mag intake and absorption, decreased mag output
Hypermagnesemia s and s
lethargy, bradycardia, hypotension, flushing, respiratory depression, cardiac arrest, prolonged PR interval
Hypermagnesemia treatment
diuretics and dialysis, calcium gluconate