Affinity Curve Shifts

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7 Terms

1
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If the curve shifts RIGHT….is affinity increased or decreased?

Decreased

2
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What are the causes of the affinity curve shifting RIGHT?

  • increased CO2

  • Increased temp

  • Increased 2,3-DPG

  • Decreased pH

3
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What is the effect of the affinity curve shifting RIGHT?

O2 molecules unload to tissues more easily

4
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When curve shifts LEFT…does affinity increase or decrease?

INCREASE

5
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What are the causes of a LEFT curve shift?

  • decreased CO2

  • Decreased temp

  • Decreased 2,3 BPG

  • Increased pH

6
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What are the effects of a LEFT curve shift?

O2 is bound tightly, hard to unload

7
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What combo indicates CO poisoning?

  • decreased O2 capacity

  • LEFT curve shift