Germ and Somatic Cells

What are somatic mutations?

Mutations in body cells (e.g. skin or muscle cells) not passed to offspring.

Which cells are affected by somatic mutations?

Only tissues derived from the mutated cell.

When are somatic mutations acquired?

During an individual's lifetime.

What disease can somatic mutations cause?

Cancer.

What are germline mutations?

Mutations in gametes passed to offspring.

Which cells are affected by germline mutations?

All cells in the offspring's body.

What is the hereditary consequence of germline mutations?

They can increase offspring cancer risk or genetic disease.