Glycolysis

BCH 351

Reaction 1: Hexose Stage

Glucose Converted to Glucose 6-phosphate

Enzyme: Hexokinase: a transferase

1st ATP Hydrolyzed

Reaction 2: Hexose Stage

Glucose 6-phosphate (Aldose) converted to Fructose 6-phosphate (Ketose)

Enzyme: Glucose 6-phosphate Isomerase: a Isomerase

Reaction 3: Hexose Stage

Fructose 6-phosphate converted to Fructose 1,6 bisphosphate

Enzyme: Phosphofructokinase-1: a transferase

2nd ATP in glycolysis used

Reaction 4: Transition Reaction

Fructose 1,6 bisphosphate converted to Dihydroxyacetone phosphate and Glyceraldehyde 3-phosphate

Enzyme: Aldolase: A lyase

Reaction 5: Triose stage

Dihydroxyacetone phosphate converted to Glyceraldehyde 3-phosphate

Enzyme: Triose Phosphate Isomerase: An Isomerase

Reaction 6: Triose stage

Glyceraldehyde 3-phosphate converted to 1,3-Bisphosphoglycerate

Enzyme: Glyceraldehyde 3-phosphate dehydrogenase: an oxidoreductase

First step of energy generation

Reaction 7: Triose stage

1,3-Bisphosphoglycerate converted to 3-Phosphoglycerate

Enzyme: Phosphoglycerate Kinase: a transferase

1st ATP produced

Reaction 8: Triose stage

3-Phosphoglycerate converted to 2-Phosphoglycerate

Enzyme: Phosphoglycerate mutase: an isomerase

Reaction 9: Triose Stage

2-Phosphoglycerate converted to Phosphoenolpyruvate

Enzyme:Enolase: an Lyase

Requires Mg2+

Reaction 10: Triose stage

Phosphoenolpyruvate converted to Pyruvate

Enzyme: Pyruvate Kinase: A transferase

2nd ATP produced