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edema
condition in which body tissues contain excessive amounts of fluid
exophthalmos
condition in which the eyeballs protrude, such as in Graves’ disease; generally caused by overproduction of thyroid hormone
gynecomastia
development of breast tissue in males; may be symptom of adrenal feminization
hirsutism
condition of having excessive amount of hair; generally used to describe females who have adult male pattern of hair growth; can be result of hormonal imbalance
hyperglycemia
condition of having high levels of sugar in the blood; associated with diabetes mellitus
hypoglycemia
condition of having low levels of sugar in the blood
hyperkalemia
condition of having high levels of potassium in the blood
hyponatremia
condition of having low level of sodium in the blood
hyposecretion
deficient hormone production by an endocrine gland
obesity
having abnormal amount of fat in the body
syndrome
group of symptoms and signs that when combined, present clinical picture of disease or condition
Addison’s disease
results from deficiency in adrenocortical hormones; there may be increased pigmentation of skin, generalized weakness, and weight loss
adrenal feminization
development of female secondary sexual characteristics (such as breasts) in a male; often result of increased estrogen secretion by the adrenal cortex
adrenal virilism
development of male secondary sexual characteristics in female often as result of increased androgen secretion by the adrenal cortex
cushing’s syndrome
set of symptoms caused by excessive levels of cortisol due to high doses of corticosteriods drugs and adrenal tumor
pheochromocytoma
usually benign tumor of the adrenal medulla that secretes epinephrine; symptoms include anxiety, heart palpitations, dyspnea, profuse sweating, headache, and nausea
diabetes mellitus
chronic disorder of carbohydrate metabolism resulting hyperglycemia and glycosuria; there are two distinct forms of diabetes mellitus: insulin-dependent diabetes mellitus (IDDM) or type 1, and non-insulin-dependent diabetes mellitus (NIDDM) or type 2
diabetic retinoplasty
Secondary complication of diabetes that affects blood vessels of the retina, resulting in visual changes and even blindness
insulin-dependent diabetes mellitus
Also called type 1 diabetes mellitus; develops early in life when the pancreas stops insulin production; patient must take daily insulin injections
insulinoma
Tumor of the islets of Langerhans cells of the pancreas that secretes excessive amount of insulin
ketoacidosis
acidosis due to excess of acidic ketone bodies (waste products); serious condition requiring immediate treatment as it may result in death for diabetic patient if not reversed; also called diabetic acidosis
non-insulin-dependent mellitus
Also called type 2 diabetes mellitus; typically develops later in life; the pancreas produces normal to high levels of insulin, but cells fail to respond to it; patients may take oral hypoglycemics to improve insulin function or may eventually have to take insulin
Recklinghausen disease
excessive production of parathyroid hormone resulting in degeneration of bones
tetany
Nerve irritability and painful muscle cramps resulting from hypocalcemia; hypoparathyroidism is one cause of tetany
acromegaly
Chronic disease of adults that results in elongation and enlargement of bones of head and extremities; can also be mood changes; due to excessive amount of growth hormone in adult
diabetes insipidus
Disorder caused by inadequate secretion of antidiuretic hormone by posterior lobe of the pituitary gland; may be polyuria and polydipsia
panhypopituitarism
Deficiency in all hormones secreted by the pituitary gland; often recognized because of problems with glands regulated by the pituitary—adrenal cortex, thyroid, ovaries, and testes
thymoma
tumor in the thymus gland
cretinism
Congenital condition in which lack of thyroid hormones may result in arrested physical and mental development'; now called congenital hypothyroidism
goiter
enlargement of the thyroid gland
Graves’ disease
Condition that results in overactivity of the thyroid gland and can cause a crisis situation; symptoms include exophthalmos and goiter; a type of hyperthyroidism
Hashimoto’s thyroiditis
chronic autoimmune form of thyroiditis; results in hyposecretion of thyroid hormones
myxedema
Condition resulting from hyposecretion of the thyroid gland in adult; symptoms can include swollen facial features, edematous skin, anemia, slow speech, drowsiness, and mental lethargy
thyrotoxicosis
Condition resulting from marked overproduction of the thyroid gland; symptoms include rapid heart action, tremors, enlarged thyroid gland, exophthalmos, and weight loss
adenocarcinoma
Cancerous tumor in gland that is capable of producing hormones secreted by that gland; one cause of hypersecretion pathologies
triiodothyronine
T3
thyroxine
T4
fasting blood sugar
Blood test to measure amount of sugar circulating throughout body after 12-hour fast
glucose tolerance test
Test to determine blood sugar level; measured dose of glucose is given to a patient either orally or intravenously; blood samples are then drawn at certain intervals to determine ability of patient to use glucose; used for diabetic patients to determine insulin response to glucose
protein-bound iodine test
Blood test to measure concentration of thyroxine (T4) circulating in bloodstream; iodine becomes bound to protein in blood and can be measured; useful in establishing thyroid function
radioimmunoassay
blood test that uses radioactivity tagged hormones and antibodies to measure quantity of hormone in the plasma
two-hour postprandial glucose tolerance test
Blood test to assist in evaluating glucose metabolism; patient eats high-carbohydrate diet and then fasts overnight before test; then blood sample is taken two hours after a meal
thyroid scan
Test in which radioactive iodine is administered that localizes in the thyroid gland; gland can then be visualized with scanning device to detect pathology such as tumors