- Methane from CO2, acetate, or methanol
- Produces Coenzyme M, Coenzyme F420, Coenzyme F430, MP, MF, CoM, CoB (C1 careers)
- Creates a sodium motive pump for ATP production
- **H is e- donor and CO2 is e- acceptor + carbon source
- Strictly anaerobic process
- Obligate anaerobes
- thermophiles, mesophiles, etc
Habitats: anoxic enviro, wetlands, animal digestive tracts, landfills, wastewater, hydrothermal vents