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What are the two main layers of the skin? Which layer is not technically part of the skin?
Epidermis and Dermis
The hypodermis is not technically part of the skin (made of adipose/fat tissue to connect the skin)
What is the relationship between melanocytes and skin color?
- all humans have an equal amount of melanocytes
- skin color depends on two causes:
1. type of melanin produced
2. how much melanin produced
What is the function of the acid mantle?
Slows bacterial growth
What is the relationship between UV rays and Vitamin D?
When exposed to UV rays, our skin helps produce vitamin D (which helps the digestive tract in absorbing muscle)
Texture of hair vs. shape of hair follicle
- Straight = Round hair follicle
- Wavy = Oval hair follicle
- Curly = flat hair follicle
What are considered the skin appendages?
- sweat glands
- oil glands
- hair
- nails
What percent of your body weight consists of skin?
15% (2.2 square meters)
What are the two layers of the dermis?
Papillary layer & reticular layer
Papillary Layer
Superficial, thin layer of the dermis (top 1/5)
- Dermal papillae
- Meissner's corpuscles
- Capillary loops
- Free nerve endings
Reticular Layer
Deeper, thick layer of the dermis (bottom 4/5)
- Hair follicle
- Arrector pili muscle
- Sebaceous gland
- Sudoriferous gland
- Pacinian corpuscle
Hypodermis
subacutaneous layer
- adipose tissue
- sensory nerve
- motor nerve
- blood vessels
Dermal Papillae
"skin nipples"
bumps that bind epidermis and dermis
creates fingerprints
Meissner's corpuscle
sense light touch
Capillary loops
where oxygen and nutrients are dropped off in the dermis (shared with epidermis)
where CO2 and waste are removed from the dermis
Free Nerve Endings
sense pain, heat, cold, itching, and tickling
Hair follicle
tunnel where the hair grows from
Arrector pili muscle
contracts to raise hair on end
Sebaceous gland
oil glands
oil is called sebum
Pacinian corpuscle
sense heavy touch (pressure/vibration)
Adipose tissue
adheres skin to underlying muscle (anchored loosely enough to allow skin to slide)
insulates heat
absorbs shock
Sensory nerve
sends messages from the merkel cells, meissner's corpuscles, free nerve endings, and pacinian corpuscles to the brain
Motor nerve
sends messages from the brain to the arrector pili muscles, sebaceous glands, sudoriferous glands
Blood vessels
delivers blood to and from the skin
artery: drops off blood with oxygen and nutrients
vein: takes away blood with CO2 and waste
Which epidermis layers contain dead keratinocytes?
Stratum corneum and lucidum
Which epidermis layer contains cells undergoing mitosis?
Stratum basale
Which layer appears spiny and why?
Stratum spinosum because keratinocytes are connected by desmosomes
What is the function of merkel cells?
sense light touch
What is the function of langerhan cells?
ingest foreign substances and activate the immune system
Which cells are formed in the bone marrow?
langerhan cells
What is the most common epidermal cell?
Keratinocytes
Which cells are stimulated by friction?
keratinocytes
What is the function of lamellar bodies?
secretes lipids that cause skin to be water resistant and prevent water loss
What type of tissue is the epidermis made of?
stacked epithelial tissues
What type of tissue is the dermis made of?
connective tissue filled with collagen and elastin fibers
Which epidermal cell has squamous anucleate cells, and what does that mean?
The stratum corneum has 20-30 layers of these cells, meaning there is no nucleus
What structure contracts to raise hair on the end?
arrector pili muscle
What structure creates fingerprints?
dermal papillae
What structure absorbs shock?
adipose tissue
What structure is the tunnel where hair grows from?
hair follicle
What structure senses heavy touch?
pacinian corpuscle
What structure senses pain?
free nerve endings
What are two ways that your skin responds to cold to maintain body warmth?
1. Blood vessels constrict
2. Blood vessels deepen to trap heat
What is the function of the sebum?
- Soften and lubricate the hair/skin
- prevent water loss
- bactericidal action (kills bacteria)
How is the skin a physical barrier?
- epidermis = stratified and keratinized
- lipids secreted by lamellar bodies cause skin to be water resistant and prevent water loss
How is the skin a chemical barrier?
- our skin's surface teems with bacteria, so the skin secretes an acid mantle, which slows bacterial growth
- sweat and sebum have ingredients that kill bacteria
- melanin acts as a shield over epidermal cells to prevent UV ray damage
How is the skin a biological barrier?
- langerhans cells ingest foreign invaders and notify the immune system, calling in other immune cells and triggering an immune response
3 Types of Skin Cancer
- Basal cell carcinoma (BCC)
- Squamous cell carcinoma (SCC)
- Melanoma
Basal Cell Carcinoma (BCC)
- The most common type, originating in basal cells at -- Often looks like a small, shiny, skin-colored or pink bump, a sore that doesn't heal, or a reddish patch.
- Slow-growing and rarely spreads.
Squamous Cell Carcinoma (SCC)
- The second most common type, developing in squamous cells of the epidermis.
- May appear as a firm, red bump or a scaly, rough patch.
- Can grow more quickly and has a higher likelihood of spreading than BCC if not treated.
Melanoma
- Develops in melanocytes, the cells that produce skin pigment.
- Often looks like a mole but can be asymmetrical, have irregular borders or multiple colors, and changes over time.
- The most dangerous form, as it can spread rapidly to other organs.