PHARM: Block 3 Drug Names

5.0(1)
studied byStudied by 26 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/120

flashcard set

Earn XP

Description and Tags

Asthma drugs, antihistamines, antianginals, nutraceuticals (only red text), diuretics, antihypertensives

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

121 Terms

1
New cards

Acetazolamide

Diuretics
Carbonic Anyhydrase Inhibitor - block reabsorption of HCO3-

*PROTOTYPE OF THIS CLASS

2
New cards

Brinzolamide

Diuretics
Carbonic Anyhydrase Inhibitor - block reabsorption of HCO3-

3
New cards

Dorzolamide

Diuretics
Carbonic Anyhydrase Inhibitor - block reabsorption of HCO3-

4
New cards

Dichlorphenamide

Diuretics
Carbonic Anyhydrase Inhibitor - block reabsorption of HCO3-

5
New cards

Furosemide

Diuretics
Loop Diuretic - inhibit NaCl resabsorption in TAL

6
New cards

Butametanide

Diuretics
Loop Diuretic - inhibit NaCl resabsorption in TAL

7
New cards

Torsemide

Diuretics
Loop Diuretic - inhibit NaCl resabsorption in TAL

8
New cards

Vasopressin
Desmopressin

Diuretics
ADH Agonists

9
New cards

Lithium

Diuretics
ADH Antagonist - Inhibit effect of ADH by blocking the making of porins

10
New cards

Demeclocycline

Diuretics
ADH Antagonist - Inhibit effect of ADH by blocking the making of porins

11
New cards

Conivaptan

Diuretics
ADH Antagonist - Inhibit effect of ADH by blocking the making of porins

12
New cards

Tolvaptan

Diuretics
ADH Antagonist - Inhibit effect of ADH by blocking the making of porins

13
New cards

Bendroflumethiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

14
New cards

Chlorothiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

15
New cards

Hydrochlorothiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

16
New cards

Hydroflumethiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

17
New cards

Methyclothiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

18
New cards

Polythiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

19
New cards

Trichlormethiazide

Diuretics
Thiazides - Inhibit NaCL transport in DCT

20
New cards

Chlorthialidone
Indapamide
Metolazone
Quinethazone

Diuretics
Sulfonamides similar to Thiazides

21
New cards

Spironolactone

Diuretics
K+ Sparing Diuretic - Aldosterone antagonist (STEROID)- will cause inhibition of Na/K ATPase activity

22
New cards

Eplerenone

Diuretics
K+ Sparing Diuretic - Aldosterone antagonist (STEROID)- will cause inhibition of Na/K ATPase activity

23
New cards

Finerenone

Diuretics
K+ Sparing Diuretic - Aldosterone antagonist (STEROID) - will cause inhibition of Na/K ATPase activity

24
New cards

Amiloride

Diuretics
K+ Sparing Diuretic - Na+ channel blocker (NON-STEROID) - will directly inhibit Na+ channels (coupled to K+ secretion)

25
New cards

Triamterene

Diuretics
K+ Sparing Diuretic - Na+ channel blocker (NON-STEROID) - will directly inhibit Na+ channels (coupled to K+ secretion)

26
New cards

Mannitol

Diuretics
Osmotic Diuretics - enhance water excretion in water-permeable segements (PCT and descending limb)

27
New cards

Canagliflozin

Diuretics

SGLT2 Inhibitors - inhibit SGLT2 transporter, interrupting reabsorption of glucose in PCT

28
New cards

Dapagliflozin

Diuretics

SGLT2 Inhibitors - inhibit SGLT2 transporter, interrupting reabsorption of glucose in PCT

29
New cards

Empagliflozin

Diuretics

SGLT2 Inhibitors - inhibit SGLT2 transporter, interrupting reabsorption of glucose in PCT

30
New cards

Caffeine

Diuretics

A1 Antagonist - will interefere with activation of NHE3 in PCT, blocking adenosine-mediated enhancement of K+ secretion in collecting tubule

Asthma Drugs - Bronchodilators

Methylxantine - PDE inhibitor (increased cAMP and cGMP) and adenosine receptor antagonist (SM relaxation)

31
New cards

Theophylline

Diuretics

A1 Antagonist - will interefere with activation of NHE3 in PCT, blocking adenosine-mediated enhancement of K+ secretion in collecting tubule

Asthma Drugs - Bronchodilators

Methylxantine - nonselective PDE 3,4,5 inhibitor, will increase cAMP levels in all cells

32
New cards

Epinephrine

Ephedrine

Asthma Drugs - Bronchodilators

Sympathomimetics - increase release of NE

33
New cards

Albuterol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

34
New cards

L-Albuterol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

35
New cards

Metaproterenol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

36
New cards

Terbutaline

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

37
New cards

Pirbuterol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

38
New cards

Salmeterol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

39
New cards

Formoterol

Asthma Drugs - Bronchodilators

Beta-2 Selective Agonists - increased intracellular cAMP and subsequent smooth muscle relaxation

40
New cards

Theobromine

Asthma Drug - Bronchodilators

Methylxantine - PDE inhibitor (increased cAMP and cGMP) and adenosine receptor antagonist (SM relaxation)

41
New cards

Ipratropium

Asthma Drugs - Bronchodilators
Muscarinic Antagonist - blocks P-ANS bronchoconstriction and mucus release

42
New cards

Tiotropium

Asthma Drugs - Bronchodilators
Muscarinic Antagonist - blocks P-ANS bronchoconstriction and mucus release

43
New cards

Beclomethasone

Asthma Drugs - Anti-inflammatories

Glucocorticoids - Activate steroid receptor, repress gene expression of pro-inflammatory proteins, and promote expression of anti-inflammatory proteins

44
New cards

Triamcinolone

Asthma Drugs - Anti-inflammatories

Glucocorticoids - Activate steroid receptor, repress gene expression of pro-inflammatory proteins, and promote expression of anti-inflammatory proteins

45
New cards

Flunisolide

Asthma Drugs - Anti-inflammatories

Glucocorticoids - Activate steroid receptor, repress gene expression of pro-inflammatory proteins, and promote expression of anti-inflammatory proteins

46
New cards

Budesonide

Asthma Drugs - Anti-inflammatories

Glucocorticoids - Activate steroid receptor, repress gene expression of pro-inflammatory proteins, and promote expression of anti-inflammatory proteins

47
New cards

Flunisolide

Asthma Drugs - Anti-inflammatories

Glucocorticoids - Activate steroid receptor, repress gene expression of pro-inflammatory proteins, and promote expression of anti-inflammatory proteins

48
New cards

Zileuton

Asthma Drugs - Anti-inflammatories
Leukotriene Inhibitors - 5-lipoxygenase inhibitor, will decrease leukotriene production

49
New cards

Zafirlukast

Asthma Drugs - Anti-inflammatories
Leukotriene Inhibitors - LTD4 receptor antagonist (prevents leukotriene-induced bronchoconstriction)

50
New cards

Montelukast

Asthma Drugs - Anti-inflammatories
Leukotriene Inhibitors - LTD4 receptor antagonist (prevents leukotriene-induced bronchoconstriction)

51
New cards

Nedocromil

Asthma Drugs - Anti-inflammatories

Chromones - Alter Cl- function, reducing mast cell degranulation and nerve conduction in lungs mediating cough

52
New cards

Cromolyn

Asthma Drugs - Anti-inflammatories

Chromones - Alter Cl- function, reducing mast cell degranulation and nerve conduction in lungs mediating cough

53
New cards

Omalizumab

Asthma Drugs - Anti-inflammatories

Anti-IgE - Lower IgE levels

54
New cards

Diphenhydramine

Antihistamines

H1 Antagonist - 1st Gen; anti-motion sickness

55
New cards

Doxylamine

Antihistamines

H1 Antagonist - 1st Gen; Sleep aid

56
New cards

Hydroxyzine

Antihistamines

H1 Antagonist - 1st Gen

57
New cards

Chlorpheniramine

Antihistamines

H1 Antagonist - 1st Gen; OTC “cold” medicine

58
New cards

Astemizole

Antihistamines

H1 Antagonist - 2nd Gen; less CNS penetration, longer lasting due to active metabolites

59
New cards

Fexofenadine

Antihistamines

H1 Antagonist - 2nd Gen; less CNS penetration, longer lasting due to active metabolites

60
New cards

Loratadine

Antihistamines

H1 Antagonist - 2nd Gen; less CNS penetration, longer lasting due to active metabolites

61
New cards

Cetirizine

Antihistamines

H1 Antagonist - 2nd Gen; less CNS penetration, longer lasting due to active metabolites

62
New cards

Methyldopa

Antihypertensives - Sympathoplegics

CNS-Acting: Alpha 2 Agonists - can be converted to active products in nerves

63
New cards

Clonidine

Antihypertensives - Sympathoplegics

CNS-Acting: Alpha 2 Agonists

64
New cards

Prazosin

Antihypertensives - Sympathoplegics

Alpha 1 Blockers - will inhibit ligand binding, causing vascular SM relaxation

65
New cards

Terazosin

Antihypertensives - Sympathoplegics

Alpha 1 Blockers - will inhibit ligand binding, causing vascular SM relaxation

66
New cards

Doxazosin

Antihypertensives - Sympathoplegics

Alpha 1 Blockers - will inhibit ligand binding, causing vascular SM relaxation

67
New cards

Propranolol

Antihypertensives - Sympathoplegics
Beta Blockers - nonspecific beta antagonist, will cause decrease CO and renin release

Antianginals

Beta Blockers - Nonselective beta antagonist

68
New cards

Metaprolol

Atenolol

Nadolol

Antihypertensives - Sympathoplegics

Beta Blockers - Beta 1 selective antagonist


Antianginals

Beta Blockers - Beta 1 selective antagonist

69
New cards

Hydralazine

Antihypertensives - Direct Acting Vasodilators

Dilate arteries (not veins)

70
New cards

Minoxidil

Antihypertensives - Direct Acting Vasodilators

Dilate arteries (not veins), opens SM membrane K+ channels causing depolarization of SM

71
New cards

Diazoxide

Antihypertensives - Direct Acting Vasodilators

Increase K+ conductance, preventing SM contraction

72
New cards

Nitroprusside

Antihypertensives - Direct Acting Vasodilators

NO release and activation of guanylyl cyclase

73
New cards

Fenoldopam

Antihypertensives - Direct Acting Vasodilators

D1 Agonist

74
New cards

Amlodipine

Antihypertensives - Direct Acting Vasodilators

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

Antianginals

CCB: Dihydropyridines

75
New cards

Felodipine

Antihypertensives - Direct Acting Vasodilators

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

Antianginals

CCB: Dihydropyridines

76
New cards

Nimodipine

Antihypertensives - Direct Acting Vasodilators

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

Antianginals

CCB: Dihydropyridines

77
New cards

Verapamil

Antihypertensives - Direct Acting Vasodilators

Calcium Channel Blockers (Non-dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement + decrease contraction, conduction velocity and rate

Antianginals

CCB: Non-dihydropyridines

78
New cards

Diltiazem

Antihypertensives - Direct Acting Vasodilators

Calcium Channel Blockers (Non-dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement + decrease contraction, conduction velocity and rate

Antianginals

CCB: Non-dihydropyridines

79
New cards

Captopril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

80
New cards

Lisinopril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

81
New cards

Benazepril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

82
New cards

Fosinopril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

83
New cards

Moexipril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

84
New cards

Perindopril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

85
New cards

Quinapril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

86
New cards

Ramipril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

87
New cards

Trandopril

Antihypertensives - Angiotensin Production or Receptor Blockers

ACE Inhibitors - prevent binding of angiotensin I and cleavage to angiotensin II; also prevent degradation of bradykinin

88
New cards

Losartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

89
New cards

Valsartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

90
New cards

Candesartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

91
New cards

Eprosartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

92
New cards

Telmisartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

93
New cards

Olmisartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

94
New cards

Valsartan

Antihypertensives - Angiotensin Production or Receptor Blockers

Angiotensin II Receptor Antagonists (ARBs) - block AT1 receptors, prevent angiotensin II from binding and activating (no bradykinin accumulation)

95
New cards

Nifedipine

Antianginals

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

96
New cards

Isradipine

Antianginals

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

97
New cards

Nicardipine

Antianginals

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

98
New cards

Nisoldipine

Antianginals

Calcium Channel Blockers (Dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement

99
New cards

Bepridil

Antianginals

Calcium Channel Blockers (Non-dihydropyridines) - blockade of open Ca2+ channels located on SM, reduce myocardial oxygen requirement + decrease contraction, conduction velocity and rate

100
New cards

Nitroglycerin

Antianginals

NO Donors - stimulate GC to cause cGMP-induced SM relaxation via dephosphorylation of MLC = vasodilation of veins and arteries, reducing myocardial oxygen requirement