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bohr shift
occurs when the partial pressure of carbon dioxide causes haemoglobin to release oxygen into respiring tissues
carbonic acid forming
forms due to the presence of the enzyme carbonic anhydrase…CO2+H20—>H2CO3
carbonic acid dissociating
forms hydrogen carbonate and hydrogen ions…H2CO3←→H+ + HCO3-
oxygen release
hydroen ions associate with haemoglobin to form haemoglobinic acid…HB + H+—>HHb
pH changes
haemoglobin binds with H+ ions to stabilise blood pH
chloride shift
movement of chloride ions into red blood cells
hydrogen carbonate ions
formed during the dissociation of carbonic acid are transported out by transport proteins in the membrane
electrical imbalance
negatively charged chloride ions enter red blood cells to prevent cell from becoming more positive