Table 5-5

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10 Terms

1
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CR1

clears immune complexes, enhances phagocytosis, regulates C3 breakdown

2
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CR2

enhances B-cell activation, B-cell coreceptor, and retention of C3d-tagged complexes

3
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CR3

binds adhesion molecules on leukocytes, facilitates extravasation, iC3b binding enhances opsonization of immune complexes

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CR4

iC3b-mediated phagocytosis

5
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CRIg

iC3b-mediated phagocytosis and inhibition of alternative pathway

6
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C1qRp

induces T-cell activation, enhances phagocytosis

7
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SIGN-R1

enhances opsonization of bacteria by MZ macrophages

8
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C3aR

induces degranulation

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C5aR

induces degranulation, chemoattraction, acts with IL-1B and TNF-a to induce acute response, induces respiratory burst in neutrophils

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C5L2

uncertain, but likely down-regulates proinflammatory C5a