4. Angiotensin Receptor Blockers (ARBs)

what are angiotensin receptor blockers (ARBs)?

antihypertensive meds that block angiotensin II at its receptor

• reduce peripheral resistance

difference between ARBs and ACE inhibitors

ARBs have less side effects

• no persistent cough or taste changes

what med name ending helps you spot an ARB?

-tan (ex: losartan, valsartan)

examples of ARBs?

• losartan

• valsartan

how do ARBs lower blood pressure?

block angiotensin II effects → less vasoconstriction → lower peripheral resistance

what do you monitor first when giving an ARB?

blood pressure (watch for orthostatic/postural drops)

what is key teaching to prevent falls on ARBs?

change positions slowly (sitting → standing)

what electrolyte risk matters with ARBs?

hyperkalemia (high potassium (K+))

what should patients avoid with ARBs because of high potassium (K+) risk?

potassium-rich foods; potassium supplements

why cant you use ACE inhibitors and ARBs together?

they will both cause super hyperkalemia

what lab/organ function should you monitor with ARBs?

kidney/renal function (can worsen renal function)

what rare but life-threatening reaction can happen with ARBs?

angioedema (swelling of face/eyes/lips/tongue; can affect airway)

when should ARBs not be used (big contraindications/combos)?

• pregnancy

• renal impairment

• do not combine with ACE inhibitors or potassium-sparing diuretics