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Hydroiodic acid (HI)
pKa ≈ −10 (very strong acid)
Hydrobromic acid (HBr)
pKa ≈ −9 (very strong acid)
Hydrochloric acid (HCl)
pKa ≈ −8 (very strong acid)
Sulfuric acid (H₂SO₄)
pKa ≈ −3 (strong acid)
Hydronium ion (H₃O⁺)
pKa ≈ −1.7
Hydrofluoric acid (HF)
pKa ≈ 3.2 (weak acid despite HF bond)

Carboxylic acids
pKa ≈ 4–5

Protonated amines
pKa ≈ 9–11
Water (H₂O)
pKa ≈ 15.7
Alcohols
pKa ≈ 16–18

Ketones
(α-hydrogens) pKa ≈ 20–24

Amides
pKa ≈ 25
Terminal alkynes
pKa ≈ 25
Hydrogen (H₂)
pKa ≈ 35

Amines
pKa ≈ 35
Alkenes
pKa ≈ 44

Alkanes
pKa ≈ 50