Pathophysiology Module 2: Immunity Cells & Immunoglobulins

T cells

Recognition of antigens

2 Types of T cells

Regulators and Effectors

Helper T cells

Regulator; notify B cells

Suppressor T cells

Regulator; turn off antibody production

Effector T cells

Killers; cytotoxic

B cells

Encountering antigens

Types of B cells

Memory and Antibody-producing

Memory B cells

Form after initial infection to "remember" a specific pathogen and produce antibodies to fight it faster in the future

Antibody-producing B cells

Produce antibodies after initial exposure

IgG (mama->baby; Greatest)

- Cross placenta to protect fetus

- Passive immunity

- Largest amount

- Main defense against bacteria

IgE (I give Epi)

- Triggers allergic reactions

- Presence in mucous membranes and skin

IgM (Massive; Mine)

- 1st antibody made by fetus

- fights blood infections

- Large molecules; can't leave blood vessels

- Triggers production of IgG

IgA (Alien experimentation?)

- Important in local immunity

- Protects from outside exposure

- Found in membranes of respiratory & GI tracts, tears, saliva, mucous

IgD (Dispatch)

- Present on B-cells produce antibodies surfaces

- Receptor for antigens

- Activates B-cells to work