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Nociception
pain/itch
Proprioception
body position
Somatosensory System
The 5 senses”: taste, touch, hearing, smell, and sight
Nociception
Proprioception
Temperature
Pressure
Balance
Somatosensory Cortex
Located in the parietal lobe
Cortex processes and fine-tunes
sensory input to determine:
Location
Intensity
Perception of sensation
Sensory signals travel
periphery->spinal cord->thalamus >somatosensory cortex
Somatosensory System Processing
How sensory information from the skin, muscles, joints, and internal organs is
Received Sensors
mechanoreceptors, thermoreceptors, nociceptors,etc
Transmitted Sensors
sensory neurons->dorsal root ganglia->sensory
pathway
Interpretation Sensors
occurs in the thalamus and somatosensory
cortex
General somatic afferent neurons
wide distribution with distribution throughout the body
senses pain, touch, temperature
Special somatic afferent neurons
distributed throughout muscles, tendons, and joints
senses position and body movement
General visceral afferent neurons
distributed throughout visceral structures
senses fullness and discomfort
Somatosensory System
Relay information thorough out the body from the periphery to the central nervous system (CNS) using:
Sensory receptors—-Ascending Pathways—-Processing Centers
Chemoreceptors
oxygen, pH, organic molecules, osmoreceptors
Mechanoreceptors
vibration/acceleration/sound, baroreceptors
Thermoreceptors
cold and warm receptors
Photoreceptor
specialized cells located in the retina of the eye that detect light and convert it into electrical signals that are sent to the brain; rods and cones
Somatosensory Neuronal Organization
First-order neurons (out of peripheral axon to CNS)
Second-order neurons (CNS to the brainstem)
Third-order neurons (thamalus to somatosensory cortex)
Somatosensory Neurotransmission
Dorsal root ganglia fibers:
Depends on the diameter and
nerve fiber myelination
Nerve fibers involved are type
A-alpha, A-beta, A-delta, & C
A-alpha fibers
Large, Heavy myelination, Very fast, Proprioception
A-beta fibers
Large, Heavy myelination, Fast, Touch and
pressure
A-delta fibers
Small, Light myelination, Moderate
speed; Sharp, localized pain and
temperature
Anterolateral (reflexes)
Pain, temperature, crude touch
Triggers autonomic responses
Discriminative (specified sensation)
Fine touch, proprioception
Allows localization
C fibers
Very small,No myelination, Slow; Dull, aching,
burning pain and temperature
Dermatome Innervation
a single spinal nerve root, which transmits sensory information from that skin area to the spinal cord
Neurogenic/neuropathic pain
Originates within the CNS
Nociceptive pain
Noxious stimulus of pain fibers initiated in skin, joints, muscles, bones, or other internal organs
Transduction
Tissue-damaging stimuli activate nerve endings
Transmission
Message is carried from the site of injury to
the brain
Modulation
Reduces activity of transmission system
Perception
Subjective awareness (sensory, emotional,
and subjective reactions to stimuli
How do we know to feel pain?
A pain message is transmitted to the brain by specialized nerve cells known as nociceptors, or pain receptors
How do we know where the pain is?
signal of pain receptors is processed by the brain, the thalamus identifies the location and nature of the pain before sending a response back to the body to indicate the source
Pain Locations
Cutaneous
Deep
Visceral
Referred
Pain Quality
Sharp, burning, stabbing, aching, etc.
Pain Duration
Acute
Chronic
Myopia
nearsightedness
Hyperopia
farsightedness
Astigmatism
blurred vision, from irregular curve of the cornea or lens
Presbyopia
farsightedness associated with aging
Cataract
blurred vision, from clouding of the lens
Vision Function
light comes through cornea reflects on retina, rods (dim light, peripheral vision) and cones (bright light, color perception)
Vitamin C Foods
Citrus fruits, Strawberries, Kiwi, Berries ,Papaya, Mango, Cantaloupe, Bell peppers , Broccoli, Brussels sprouts, Cauliflower, Tomatoes, Potatoes, Spinach, and Kale
Vitamin A Foods for vision improvement
Carrots, Spinach, Sweet potatoes, Egg, Bell pepper, Beef liver, Mango, Apricot, Cantaloupe
Strabismus
cross-eyed, from lack of eye muscle coordination
Nystagmus
rapid, uncontrolled eye movement, involuntary
Inner Ear Alterations in Hearing
Cochlear hair cell damage
• Tinnitus
• Sensorineural hearing loss (presbycusis)
Equilibrium disruption
• Meniere disease
Hearing Function
outer ear gathering sound waves, the middle ear amplifying them with tiny bones, and the inner ear translating them into nerve signals
External and Middle Ear Alterations in Hearing
Obstruction
• Cerumen impacted
• Mass
Inflammation
• Otitis externa/media
Barotrauma
Fibromyalgia Patho
Condition of soft tissues and
muscles
Common in AFAB, especially older
adults (60-70 years old)
Unknown cause
Cochlear implants
bypasses damage hearing cells (cochlea) caused by congenital or environmental loss
Meniere Disease
causes vertigo, neuronal hearing loss, tinnitus
Otitis externa/media
ear infection
Barotrauma
caused by a difference in pressure between a body cavity and the surrounding environment
Fibromyalgia Symptoms
Fatigue
Pain
Depression
Malaise
Fibromyalgia Diagnosis
No diagnostic test exists
Subjective assessment
History of fatigue
Chronic musculoskeletal pain for
at least 3 months
12/18 tender point sites
Trigger points (tight bands of muscle fibers)
Migraines Patho
Recurrent headaches (HA), mod-
severe that last 1-2 days
Accompanied with nausea, vomiting, and sensitivity to noise and light
Exact cause unknown
Migraine phases: Prodrome
mood changes, food cravings, neck stiffness in hours to days before HA
Migraine phases: Aura
not common, visual disturbances preceding the HA
Migraine phases: Headache
pain, unilateral, pulsing, throbbing
Migraine phases: Postdrome
fatigue, inability to concentrate, depressed or euphoric mood
Migraines Diagnosis
History
Physical exam
MRI/CT (rule out masses or lesions in brain)
Meniere Disease Patho
Altered vestibular function
Membranous labyrinth swelling (compresses bony labyrinth)
Increased volume of endolymph
causes dilation altering hearing and
balance
Unilateral occurrence
Meniere Disease Clinical Manifestations
Vertigo, nausea and vomiting, sensorineural hearing loss, pressure/pain, tinnitus and
nystagmus
Meniere Disease Diagnosis
History
Physical exam
Auditory and visual tests
Macular Degeneration Patho
Degeneration of the fovea
Distorted central vision
Drusen deposits
Choroidal neovascularization
Dry (atrophic) Macular Degeneration
slow progression of symptoms
Wet (exudative) Macular Degeneration
typically rapid and severe vision loss
Macular Degeneration Clinical Manifestations
Difficulty reading, recognizing faces, or colors
Blindness
seeing detail
severity—loss of vision
Macular Degeneration Risk Factors
60 years or older
Smoking
Hypertension
Being overweight or obese
Family history
Macular Degeneration Diagnosis
Vision screenings
Ophthalmoscopic exam
Leakage (wet)
Bulging macula (wet)
Drusen deposition (dry)