Glycolysis Rxns

Glycolysis Formula

Glucose + 2 NAD+ + 2 ADP + 2 Pi → 2 Pyruvate + 2 NADH + 2 ATP + 2 H2O

glycolysis location

cytosol of cells

1st enzyme in glycolysis

Hexokinase

Hexokinase function

transfers organic phosphate from ATP to carbon 6 of glucose

2nd Enzyme in glycolysis

Phosphoglucoisomerase

Phosphoglucoisomerase function

creates an isomer w/ carbon 1 out of the ring

3rd enzyme of glycolysis

Phosphofructokinase (PFK)

Phosphofructokinase (PFK) function

organic phosphate on carbon 1

4th enzyme of glycolysis

Aldolase

Aldolase function

cuts 6 carbon sugar into 2 3-carbon sugars

5th enzyme in glycolysis

Isomerase

Function of isomerase

catalyzes the reversible interconversion DHAP and GAP

6th Enzyme in glycolysis

GAP Dehydrogenase

GAP Dehydrogenase function

oxidizes GAP, transferring a hydride to NAD+ to generate NADH and H+, and simultaneously phosphorylates the molecule, forming 1,3-BPG

7th Enzyme in glycolysis

phosphoglycerokinase

phosphoglycerokinase function

catalyzes the transfer of a phosphate group from 1,3-bisphosphoglycerate to ADP, producing ATP and 3-phosphoglycerate (3PG)

8th enzyme in glycolysis

phophoglyceromutase

phosphoglyceromutase function

catalyzes the reversible conversion of 3-phosphoglycerate to 2-phosphoglycerate (3PG → 2PG)

9th enzyme in glycolysis

Enolase

Enolase function

catalyzes the dehydration of 2-phosphoglycerate to form phosphoenolpyruvate (PEP)

10th enzyme in glycolysis

Pyruvate kinase

pyruvate kinase function

catalyzes the irreversible conversion of phosphoenolpyruvate (PEP) to pyruvate, generating a molecule of ATP

End Product of Glycolysis

Pyruvate