Fluoride, Herbals, and Nicotine

Name 3 uses of fluoride:

a.

b.

c.

Name 3 uses of fluoride:

a. antimicrobial

b. anticaries

c. osteoporosis

Give 4 signs/symptoms of fluoride overdose:

a.

b.

c.

d.

Give 4 signs/symptoms of fluoride overdose:

a. muscular weakness, spasms, paresthesia

b. CNS depression

c. bronchospasm

d. ventricular fibrillation, cardiac arrest

How is a fluoride overdose of < 2.3mg/lb of body weight treated?

provide calcium (milk)

How is a fluoride overdose of > 2.3mg/lb of body weight treated?

• induce vomiting

• give orally-soluble calcium (mild 5% calcium gluconate or calcium lactate solution)

• seek immediate assistance

Name 3 “natural” products that may cause excessive or prolonged bleeding during a dental hygiene procedure:

a.

b.

c.

Name 3 “natural” products that may cause excessive or prolonged bleeding during a dental hygiene procedure:

a. ginger, ginko, ginseng, garlic, fish oil

b. Saint-John’s Wort

c. glucosamine/chondroitin

Name 5 functions of nicotinic receptors:

a.

b.

c.

d.

e.

Name 5 functions of nicotinic receptors:

a. improves mood, reduces anxiety, antidepressant properties, activates reward pathways to induce feelings of pleasure (increases levels of dopamine)

b. pain processing

c. appetite suppressant

d. cognitive functions, stimulates memory, alertness, and focus

e. increases HR, BP

The endogenous agonist of nicotinic receptors is ___________________.

The endogenous agonist of nicotinic receptors is acetylcholine.

Nicotine is a parasympatho_________ that ___________ acetylcholine.

Nicotine is a parasympathomimetic that mimics acetylcholine.

Curare is a parasympatho_________ that ______________ acetylcholine.

Curare is a parasympatholytic that blocks acetylcholine.

Name the 2 non-nicotine drugs used for tobacco cessation:

a.

b.

Name the 2 non-nicotine drugs used for tobacco cessation:

a. Bupropion (Zyban)

b. Varenicline (Chantix)