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What is the pathway of the closed transport system
Heart → large arteries → medium arteries → arterioles → capillary beds → venules → medium veins → large veins → heart
Where do substances diffuse across
Capillary walls
O2 and nutrients travel from ___ to ___
blood, tissues
Waste and CO2 travel from ___ to ___
tissues, blood
Tunica intima structure
Thin layer of endothelium, CT basement membrane
Tunica media structure and function
Circularly arranged smooth muscle and elastic CT. Allows for changes in lumen diameter
Tunic adventitia/externa structure and function
Areolar or fibrous CT. Protects and anchors vessels.
Arteries expand during ___ and recoils passively during ____
systole, diastoleae
Elastic arteries or “conducting vessels” traits
large, close to the heart, most expandable
Muscular arteries or “distributing vessels” traits
medium-sized, named arteries in the body
Arterioles traits
Smallest, “resistance vessels”
function of capillaries
provide for exchange of materials in tissues
capillaries traits
narrowest vessels, walls = endothelium (one cell layer)
what percentage of blood volume is in the veins?
65
Why are veins low pressure vessels
Thin walls and large lumens
What are the 3 mechanisms for venous return of blood to the right atrium?
Valves, skeletal muscle pump, respiratory pump
valves structure and function
formed by folds of tunica intima and highly concentrated in limbs; prevents back flow
The heart pumps blood through arteries (away), but pressure is ___ when blood reaches the veins
low
how does the skeletal muscle pump work
skeletal muscle contractions squeeze veins
Some pressure from blood comes from ____
capillary beds
What causes blood to flow from veins in the abdominal region to veins in the thoracic region?
The respiratory pump causes an increase in intra abdominal pressure and a decrease in intra thoracic pressure during respiration
The aorta leaves from the ____ of the heart
left ventricle
ascending aorta leaves the __
left ventricle
aortic arch arches to the ___
left
thoracic aorta travels downward through the ___
thorax
abdominal aorta passes through the ___ into the ___ cavity
diaphragm, abdominopelvic cavity
ascending aorta branches
right and left coronary arteries, serves the heart/myocardium
braciocephalic trunk branches
right common carotid after and right subclavian artery
left common carotid artery branches
internal and external carotid arteries
left subclavian artery branches
left vertebral artery and continues as the axillary artery → brachial artery → radial and ulnar arteries
what do intercostal arteries supply
muscles of the thorax wall
what do bronchial arteries supply
lungs
What do esophageal arteries serve
esophagus
What do phrenic arteries serve
diaphragm
what is the first branch from the abdominal aorta? what are its three branches?
celiac trunk branches into the left gastric artery, splenic artery, and common hepatic artery
hepatic artery serves the
liver
Superior mesenteric artery
most of the small intestine and first half of large intestine
Left and right renal arteries – serves the
kidneys
Left and right gonadal arteries
ovarian in females, testicular in males
Lumbar arteries serve
muscles of the abdomen and trunk
Inferior mesenteric artery
supplies the second half of the large intestine
what are the final branches of the aorta
Left and right common iliac arteries
Internal iliac arteries serve the
pelvic organs
External iliac arteries enter the thigh → ____
femoral artery → popliteal artery → anterior and posterior tibial arteries
Blood in the heart chambers ___ nourish the myocardium
does NOT
Blood empties into the ____ via the ___
right atrium, coronary sinus
What makes up the heart’s nourishing circulatory system?
Coronary arteries, cardiac veins, and the coronary sinus
Where do coronary arteries branch from? function?
Branch from the aorta and supply the heart muscle with oxygenated blood
What do cardiac veins do?
Drain deoxygenated blood from the myocardium
What is the coronary sinus?
A large vein on the posterior of the heart that receives blood from cardiac veins
Where do arteries originate?
behind aortic semilunar valves
What do interarterial anastomoses do?
assure continued blood supply by providing alternate pathways for blood flow if an artery is blocked
Function of capillary beds around alveoli
permit gas exchange (exchange CO2 for O2)
what is blood supply for the lungs provided by
bronchial arteries
Veins of hepatic portal circulation drain the:
• Digestive organs
• Spleen
• Pancreas
Major vessels of hepatic portal circulation
• Inferior and superior mesenteric
veins
• Splenic vein
• Left gastric vein
Function of Capillary beds of the digestive system
absorb nutrients and toxins
What carries blood from the digestive system to the liver?
hepatic portal vein
What is the liver’s role in the hepatic portal system?
Maintain proper glucose, fat, and protein concentration in blood, and filters toxins
What happens to blood after it leaves the liver?
drains into the hepatic vein
What is another name for the cerebral arterial circle?
Circle of Willis
What do internal carotid arteries branch into?
Anterior and middle cerebral arteries which supply most of the cerebrum
Vertebral arteries join within the skull to form the ____
basilar arteries
What does the basilar artery supply?
Brain stem and cerebellum
What do posterior cerebral arteries come from?
Division of the basilar artery
What do posterior cerebral arteries supply?
Posterior cerebrum
What connects anterior and posterior blood supply in the brain?
Communicating arteries
Where do the Superior and inferior vena cava enter?
the right atrium of the heart
Superior vena cava drains the ___
head and arms
Inferior vena cava drains the ____
lower body
Trace deep venous return from the arm
Radial & ulnar veins→ brachial vein→ axillary vein
What does the cephalic vein do?
Drains lateral arm and empties into axillary vein
What does the basilic vein do?
Drains medial arm and empties into brachial vein
Where are basilica and cephalic veins jointed?
At the median cubital vein (elbow area)
Where does the subclavian vein receive venous blood from?
axillary vein & skin and muscles of an head an neck via external jugular vein
What does the vertebral vein drain?
The posterior part of the head
What does the internal jugular vein drain?
the dural sinuses of the brain
Where do brachiocephalic veins receive venous blood from?
Subclavian, vertebral, and internal jugular veins
What forms the superior vena cava?
Left & right brachiocephalic veins
What does the azygos vein drain?
Thorax
What veins drain the legs?
Anterior/posterior tibial and fibular veins
Trace deep venous return from the leg
Posterior tibial → popliteal → femoral → external iliac
What does the great saphenous vein (longest veins of the body) do?
Receive superficial drainage of the legs
How are the common iliac veins (left and right) formed?
Internal + external iliac veins on its own side
Where does the right gonadal vein drain?
the right ovary in females and the right testicle in males
Where does the left gonadal vein drain?
Left renal vein
What do renal veins drain?
kidneys
What does the hepatic portal vein do?
drains the digestive organs and travels through the liver before it enters systemic circulation
What do hepatic veins drain?
the liver
What is the function of the placenta?
Fetus receives exchanges of gases nutrients, and wastes
What does the umbilical vein carry?
Blood rich in nutrients and oxygen to the fetus
What do the rei umbilical arteries carry?
carbon dioxide and debris-laden blood from fetus to placenta
In fetal circulation, blood flow bypasses the liver through the ___ and enters the ____
ductus venosus, inferior vena cava
In fetal circulation, what does the foramen ovale do?
Shunts blood from the right atrium → left atrium (bypasses lungs)
In fetal circulation, what does the ductus arteriosus do?
connects the aorta and pulmonary trunk (becomes ligaments arteriosum at birth)
Where does a simple “tube heart” (without chambers) develops?
in the embryo
When does the simple tube heart start pumping?
Week 4 post-fertilization
When does the heart become a four-chambered organ?
end of week 7 post-fertilization
When do most structural changes (of the circulatory system) in the fetus stop?
after the seventh week post-fertilization