Primary Herpetic Gingivostomatitis

Determine the disease

Primary Herpetic Gingivostomatitis

Common oral disease which develops in both children and young adult

Primary Herpetic Gingivostomatitis

Primary Herpetic Gingivostomatitis develops in both [?] and [?]

children

young adult

Who suggested that the primary form is probably more common in older adults? (HSV1)

sheridans and hermann

Sheridans and hermann suggested that primary form is probably more common in [?], (?)

older adults

HSV1

Clinical features of Primary Herpetic Gingivostomatitis (x7)

• Develops in both children and young adults

• Rarely occurs before 6 months because of the circulating antibodies in the infant derived from the mother

• The disease occurring in children is frequently the primary attack and is characterized by development of fever, irritability, headache, pain upon swallowing and regional lymphadenopathy

• Within few days mouth become painful and the gingiva intensely inflamed

• The lips, tongue, buccal mucosa, pharynx, and tonsils may also be involved, Shortly, yellowish fluid filled vesicle develop. These ruptures and form shallow, ragged extremely painful ulcers covered by fray membrane and covered by an erythematous halo 

• The gingival inflammation precedes the formation of ulcers by several days. The ulcers vary in size, from tiny to several millimeter in diameter

• They spontaneously within 7-14 days and leave no scar

Could be isolated from facial, labial, and oral herpetic lesions for 2-6 days

HSV1

Could be isolated from genital lesions for 2-14 days

HSV2

HSV1 could be isolated from [?] for 2-6 days

facial, labial, and oral herpetic lesion

HSV1 could be isolated from facial, labial, and oral herpetic lesions for [?]

2-6 days

HSV2 could be isolated from [?]s for 2-14 days

genital lesions

HSV2 Could be isolated from genital lesions for[?]

2-14 days

Could be isolated from patients suffering from a gingivostomatitis with particular clinical configuration

herpes simplex virus

histologic features of primary herpetic ginginvostomatitis

• Herpetic vesicle is an intraepithelial blister filled with fluid

• Degenerating cells show “ballooning degeneration”

• Other cells contains intranuclear inclusions called lipschutz bodies

• The subjacent connective tissue is usually infiltrated by inflammatory cell

• When the vesicle ruptures the surface of the tissue is covered by an exudate filled fibrin, PMNL and degenerated cells

Herpetic virus may be recovered from [?] of patient during the course of the disease

saliva

Mode of transmission of Primary Herpetic Gingivostomatitis

• Transmission may occur by droplet infection

• Direct contact with affected person

• Commonly associated with pneumonia, meningitis and common cold

• Incubation period range from 2-20 days

• Occasional epidemics in an orphanage nursery

Treatment Primary Herpetic Gingivostomatitis

• Treatment is unsatisfactory because of the disease is unalterable

• Antibiotic therapy to prevent secondary infection