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outcome of delaying therapy according to the CONCUSS study
delaying therapy for 6 weeks did not negatively impact the eventful effectiveness of OBVAM, it prolonged the period of symptoms and delayed the return to normal activities
seizure
temporary disruption of regular brain activity
Nonepileptic seizures
resemble epileptic seizures but lack abnormal brain electrical discharge. they don't respond to anti-seizure drugs and are treated with cognitive behavioral therapy
epilepsy
2+ unprovoked seizures
what lobe of the brain is most commonly associated with epilepsy
temporal lobe
a mild TBI has _____ the risk of epilepsy
double
which lobe are complex visual hallucination most commonly associated with
temporal
what treatment for epilepsy had a 90% average reduction in the group with long term implants
targeted thalamic stimulation treatment
TBI, CTE and acute enecphalopathy can lead to endocrine dysfunction and can therefor cause?
post-traumatic hypopituitarism --> GH deficiency
magnocellular pathway
unconscious information on motion, depth, and brightness and pre-conscious body preparation and posture for movement.
dorsal stream
layers 1 & 2 of LGN
parvocellular pathway
conscious awareness of color, recognition, perception and fine details
ventral stream
account for 80% of ganglion cells
koniocellular pathway
involved in reflexive eye and head movements
has one branch the splits into each parvo and mango pathway
egocentric localization requires?
visual components, vestibular components and postural/proprioceptive components
prosaccades
reflexive, stimulus-driven toward a target
anti-saccades
voluntary saccades away from a target, requiring suppression of reflexive prosaccade
memory-guided saccades
directed towards the location of a previously presented target
therapy for VMS, focal binding, and AEL patients
saccades
what is the most common type of saccadic intrusion and explain
Square Wave Jerks
they are small saccades from the target, followed by a short intersaccadic interval and then another saccade back to the target
what does base left yoked prisms do
corrects spatial disorientation/AEL and moves attention toward the right field of view
what does base right yoked prisms do
moves attention toward the left field of view
what does base down yoked prisms do
expands space, person leans back on their heals
what does base up yoked prisms do
grounding effect, person leans forward on their toes
what methods reduce the symptoms of focal binding
BI prism
bi-nasal occlusion
blue tint
what does low plus lenses do
reduced visual demand and stress
what is the primary marker and defining feature of CTE
accumulation of pTau protein
the localization of the protein is a critical factor between CTE and non-CTEtau
a single TBI with LOC is linked to an increase in what disease
parkinsonism
Direct Traumatic Optic Neuropathy (TON)
direct trauma to the head can cause damage to the optic nerve and dislocate it from the scleral canal.
most commonly from forehead trauma
signs of direct traumatic optic neuropathy
decreased VA, VF defect (arcuate), and normal fundus.
order a CT or MRI
indirect traumatic optic neuropathy
blunt trauma to orbit or cranium and the force damages the optic nerve.
this is the most common form and usually at the canalicular optic nerve
optic atrophy
irreversible loss of RGC axons within the optic nerve
signs: pallor or NFL wedge defects
optic nerve hypoplasia
incomplete development of the optic nerve
has a double ring sign
toxic optic neuropathy
bilateral retrobulbar optic neuropathy from meds or toxins
blue tints
good for calming, CI, accommodative spasm
increases parasympathetic
green
good for pain relief, migraine, vertigo and DAI
yellow
stimulating, increases sympathetic and decreases accommodation
pink
good for emotional fatigue, CE, accommodative excess
Rose/FL-41
good for photophobia
what is the most intense sensory depressant tint
violet
what tint triggers migraines
red
lyme disease
triad: BV dysfunction, visual processing deficits and asthenopia
visual snow syndrome
neurological disorder of central visual processing. can be associated with Lyme and COVID.
persistent visual static, floaters and after images
tx: violet tint, lamotrigine, low plus, prism
what is the outcome of a stroke in the right parietal lobe
left hemifield neglect
what % of TBI patients had strabismus
what % of cardiovascular accidents patients had strabismus
25%
35%
A pattern esotropia
more eso in upgaze
V pattern esotropia
more eso in downgaze
A pattern exotropia
more exo in downgaze
V pattern exotropia
more exo in upgaze
what should you expect if a TBI patient has a new-onset diplopia
a non-comitant deviation
post-concussion syndrome
lasts longer than 1 month after injury
30-50% of children with concussions
return to play/learn
rest: 1-2 days
return to learn: 1 week
return to play: 1-2 weeks
superior colliculus
initiates saccades
DLPFC
anti-saccades, inhibition of reflexive saccades
caudate nucleus
inhibits SNPR (allowing saccades) when FEF is active
SNPR
inhibits superior colliculus to prevent saccades
FEF
voluntary, memory guided saccades
PEF
reflexive saccades
abnormal egocentric localization
caused by neurological events disrupting the ambient process and leads to a spatial dysfunction. magno and parvo pathways don't align and therefore a midline shift is formed
focal binding
problem with the dynamic process of shifting attention between central and peripheral vision. its associated with VOR and saccadic suppression. it points to a dysfunction in control and smooth coordination of eye movements and visual attention
objective prism test
patient fixates at a distance target and high BO prism is placed in front of the "blind eye". if the patient is seeing: they should make an involuntary inward movement, while a blind eye will not
internuclear ophthalmoplegia
lesion of MLF causing ipsilateral adduction weakness and contralateral abducting nystagmus
Tolosa-Hunt syndrome
idiopathic granulomatous inflammation of the cavernous sinus causing painful ophthalmoplegia
Binasal occlusion
occludes bitemporal retina to reduce peripheral noise
van orden star test
behavioral test measuring spatial organization and identifying midline shifts
what is the purpose of the alpha omega pupil test
assess autonomic balance and sympathetic dominance
the alpha omega pupil sign is characterized by
a pupil that constricts then re-dilates or pulses
ipRGCs contain what photopigment
melanopsin
what wavelength region is melanopsin most sensitive to
480-blue
which tint is indicated for acute syndrome (post-TBI, CI)
blue or BG
which tint is best choice for chronic eso posture and low visual stamina
red/orange
FL-41 is helpful for
photophobia
fluorescent light sensitivity
blepharospasm
best tint for migraine photophobia
green
patients with visual snow respond best to
violet tint
key rule of the TBI tint tiral
subjective tint preference must align with objective phoria findings
parkinson's disease most common report increased comfort with?
blue tints
which type of patient most benefits from blue application tints that stimulate the parasympathetic system
post-concussive patients with headaches, photophobia or increased sympathetic drive