Chapter 18 Review Quiz

Which of the following statements is TRUE?

The mitotic spindle helps segregate the chromosomes to the two daughter cells.

The G₁ DNA damage checkpoint

involves the inhibition of cyclin-Cdk complexes by p21

Which word or phrase below best describes the phase in mitosis in Figure 18-29?

Metaphase

Which of the following about apoptosis is TRUE?

Apoptosis can be promoted by the release of cytochrome c into cytosol from mitochondria

Which of the following statements about kinetochores is TRUE?

Kinetochores assemble onto chromosomes during late prophase.

Disassembly of the nuclear enevelope

must occur for kinetochore microtubules to form in animal cells.

Which of the following does not occur during M phase in animal cells?

growth of the cell

Apoptosis differs from necrosis in that necrosis

causes cells to swell and burst, whereas apoptotic cells shrink and condense.

Which of the following events does NOT usually occur during interphase?

The nuclear envelope breaks down.

Progression through the cell cycle requires a cyclin to bind to a Cdk because

the binding of a cyclin to Cdk is required for Cdk enzymatic activity.

Sister chromatid separation occurs because ____ are destroyed by the APC/C

securins

Which of the following statements, about the cell cycle is FALSE?

Once a cell decides to enter the cell cycle, the time from start to finish is the same in all eukaryotic cells.

Cytokinesis in animal cells

requires ATP.

Which of the following statements is FALSE?

Cdc25 dephosphorylation of Wee1 activates the kinase, promoting the G2/M transition.

Which of the following statements is TRUE?

In anaphase B, microtubules associated with the cell cortex shorten.