Exam 2 Prototypes

Tetracycline

Prototype drug: Tetracycline (Achromycin)

Macrolide

Prototype drug: Erythromycin (Erythrocin)

Lincosamide

Prototype drug: Clindamycin (Cleocin)

Sulfonamide Derivative

Prototype drug: Trimethoprim-sulfamethoxazole (Bactrim)

Oxazolidinone

Prototype drug: Linezolid (Zyvox)

Miscellaneous Antibiotic Agent

Prototype drug: Chloramphenicol (Viceton)

Aminoglycoside

Prototype drug: Gentamicin (Garamycin)

Beta-Lactam

Prototype drug: Amoxicillin (Amoxil)

Fluoroquinolone

Prototype drug: Ciprofloxacin (Cipro)

Glycoprotein

Prototype drug: Vancomycin (Vancocin)

Lipoglycoprotein

Prototype drug: Telavancin (Vibativ)

Cyclic Lipopeptide

Prototype drug: Daptomycin (Cubicin)

Nitroimidazole

Prototype drug: Metronidazole (Flagyl)

Antimycobacterial

Prototype drug: Isoniazid (Nydrazid)

Antimycobacterial

Prototype drug: Pyrazinamide (Rifater)

Antimycobacterial (Rifamycin)

Prototype drug: Rifampin (Rifadin)

Nitrofuran

Prototype drug: Nitrofurantoin (Macrobid, Macrodantin)

Allylamine (Antifungal)

Prototype drug: Terbinafine (Lamisil)

Azole Derivative (Antifungal)

Prototype drug: Ketoconazole (Nizoral)

Polyene Macrolide (Antifungal)

Prototype drug: Amphotericin B (Fungilin)

Antiprotozoal Agent

Prototype drug: Metronidazole (Flagyl)

Antimalarial Agent

Prototype drug: Chloroquine (Aralen)

Anthelmintic Agent

Prototype drug: Ivermectin (Stromectol)

Ectoparasiticide Agent

Prototype drug: Permethrin (Nix)

Neuraminidase Inhibitor (Antiviral)

Prototype drug: Oseltamivir phosphate (Tamiflu)

Polymerase Acidic Endonuclease Inhibitor (Antiviral)

Prototype drug: Baloxavir marboxil (Xofluza)

Protease Inhibitor (Antiviral)

Prototype drug: Ritonavir (Norvir/Paxlovid)

Nucleoside Analogue (Antiviral)

Prototype drug: Acyclovir sodium (Zovirax)

Nucleoside Reverse Transcriptase Inhibitor (NRTI)

Prototype drug: Zidovudine (Retrovir)

Alkylating Agent: Nitrogen Mustard

Prototype drug: Cyclophosphamide (Procytox)

Alkylating Agent: Platinum Compound

Prototype drug: Cisplatin (Platinol)

Antineoplastic Antibiotic: Anthracycline

Prototype drug: Doxorubicin hydrochloride (Adriamycin)

Mitotic Inhibitor: Vinca Alkaloid

Prototype drug: Vincristine (Oncovin)

Antimetabolite: Folic Acid Analog

Prototype drug: Methotrexate (Trexall)

Antimetabolite: Purine Analog

Prototype drug: Mercaptopurine (Purinethol)

Gonadotropin-Releasing Hormone Agonist

Prototype drug: Leuprolide (Eligard)

Androgen Receptor Blocker

Prototype drug: Flutamide (Eulexin)

Estrogen Receptor Blocker

Prototype drug: Tamoxifen (Soltamox)

Biologic Response Modifier: Interferon

Prototype drugs: Interferon alfa-2a (Roferon A), Interferon alfa-2b (Intron A)

Leukopoietic Colony-Stimulating Factor

Prototype drug: Filgrastim (Neupogen)

Erythropoiesis Stimulating Agent

Prototype drug: Epoetin alfa (Epogen, Procrit)

Serotonin 5-HT3 Receptor Antagonist

Prototype drug: Ondansetron (Zofran)

Anticholinergic

Prototype drug: Scopolamine (Transderm Scop)

Neurokinin-Receptor Antagonist

Prototype drug: Aprepitant (Emend, Aponvie, Cinvanti)

Dopamine Receptor Antagonist

Prototype drug: Metoclopramide (Reglan)

Cannabinoid

Prototype drug: Dronabinol (Marinol)

Antihistamine

Prototype drug: Promethazine (Phenergan)

Meds to Treat GI Disorders

Antacid

Prototype drug: Calcium carbonate (TUMS)

H2 Receptor Antagonist

Prototype drug: Famotidine (Pepcid)

Proton Pump Inhibitor

Prototype drug: Omeprazole (Prilosec)

GI Protectant

Prototype drug: Sucralfate (Carafate)

Prostaglandin E Analog

Prototype drug: Misoprostol (Cytotec)

Antibiotic (H. pylori therapy)

Prototype drug: Amoxicillin (Novamoxin)

Meds to Treat Bowel Disorders

Immunomodulator

Prototype drugs: Azathioprine (Azasan, Imuran); Methotrexate (Jylamvo, Otrexup, Rasuvo, Trexall, Xatmep)

5-Aminosalicylate

Prototype drug: Sulfasalazine (Azulfidine)

Corticosteroid

Prototype drug: Prednisone (Rayos)

TNF-Alpha Inhibitor

Prototype drug: Infliximab (Avsola, Inflectra, Remicade, Renflexis)

Anticholinergic

Prototype drug: Dicyclomine (Bentyl)

Antibiotic (IBS-D)

Prototype drug: Rifaximin (Xifaxan)

5-Alpha Reductase Inhibitor

Prototype drug: Finasteride (Proscar)

Alpha-Adrenergic Receptor Antagonist

Prototype drug: Tamsulosin (Flomax)

Phosphodiesterase Type 5 (PDE-5) Inhibitor

Prototype drug: Sildenafil (Viagra)

Anticholinergic

Prototype drug: Oxybutynin (Ditropan)

Urinary Analgesic

Prototype drug: Phenazopyridine (Pyridium)

Fluoroquinolone Antibiotic

Prototype drug: Ciprofloxacin (Cipro)

Sulfonamide Antibiotic

Prototype drug: Trimethoprim-sulfamethoxazole (Bactrim)

Nitrofuran Antibiotic

Prototype drug: Nitrofurantoin (Macrobid)

Cholinergic Agonist

Prototype drug: Bethanechol (Duvoid, Urecholine)

Meds to Treat Hormonal and Reproductive Disorders

Estrogen

Prototype drugs: Estrogens/Estradiol (Delestrogen, Estrace, Depo-Estradiol, EstroGel)

Progestin

Prototype drug: Progesterone (Medroxyprogesterone acetate)

Androgen

Prototype drug: Testosterone (Depo-Testosterone, AndroGel)

Gonadotropin-Releasing Hormone Agonist

Prototype drug: Leuprolide (Lupron Depot, Camcevi, Eligard)

Gonadotropin-Releasing Hormone Antagonist

Prototype drug: Relugolix (Orgovyx)

Potassium Sparing Diuretic; Steroidal Antiandrogen

Prototype drug: Spironolactone (Aldactone, CaroSpir)

Synthetic Progesterone; Steroidal Antiandrogen

Prototype drug: Progesterone (Crinone)

5-Alpha Reductase Inhibitor

Prototype drug: Finasteride (Proscar)

Oral Contraceptive

Prototype drugs: Combination estrogen-progestin (Ortho Tri-Cyclen, Yaz)

Contraceptive (Transdermal)

Prototype drugs: Norelgestromin + Ethinyl estradiol (Xulane, Zafemy)

Contraceptive (Vaginal Ring)

Prototype drugs: Etonogestrel + Ethinyl estradiol (NuvaRing, Annovera)

Contraceptives (Hormonal)

Prototype drugs: Norethindrone (Micronor, Drospirenone); Medroxyprogesterone (Depo-Provera); Etonogestrel (Nexplanon, NuvaRing); Levonorgestrel (Mirena, Skyla, Kyleena, Plan B One-Step)

Biguanide

Prototype drug: Metformin (Glucophage)

Gonadotropin

Prototype drugs: hMG, Menopur, Repronex

Hormones - Oxytocic

Prototype drug: Oxytocin (Pitocin)

Oxytocic - Ergot Alkaloids

Prototype drug: Methylergonovine (Methergine)

Synthetic Prostaglandin

Prototype drug: Dinoprostone (Cervidil, Prepidil Gel)

Prostaglandin

Prototype drug: Misoprostol (Cytotec)

Beta-2 Adrenergic Agonist

Prototype drug: Terbutaline (Brethine)

Corticosteroid

Prototype drugs: Betamethasone, Dexamethasone (Celestone)