Lecture 2 - Size Exclusion Chromatography

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5 Terms

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The column contains

resin with small pores

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What happens to small molecules

Analytes that are SMALL will enter pores in the resin and become trapped

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What happens to large molecules

Analytes will continue to move through the column

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The ____ the analyte; the ____ it migrates

  1. Smaller, Slower

  2. Larger, Faster

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Clinical Application

Separate a sample with various proteins