Quiz 3 Molecular Genetics

origins of replication

sites that have an opening in the DNA that allows helicase to begin

Replicon

any DNA molecule under the control of one origin of replication

Ori C

fixed point where E. coli starts replicating

dnaA

E. coli initiator

Ter sites

two clusters of 23 bp sequences that bind tus proteins

Tus proteins

bind to ter sites and block the advance of replication forks in one direction

Telomeres

TG rich repeats on the ends of linear DNA to prevent important sequences from being lost after replication

Telomerase

specialized DNA polymerase that adds telomeres to DNA ends

DNA binding proteins

cover the telomeres of chromosomes and protect them, while also limiting telomere growth

transcription

copying the sequences of DNA into RNA

RNA polymerase

catalyzes transcription

Sigma factors

bind to the RNA polymerase core and directs the enzyme to promoters

Initiation