Introduction to the Immune System Learning Objectives: - Understand the role of the cells in the innate and adaptive immune system - Describe the

The first line of defense in the innate immune system includes __.

physical barriers such as the skin and epithelia.

Innate immune cells are described as __, but rapidly acting and efficient.

non-specific.

The second line of defense in the innate immune system involves __ cells.

innate immune.

Macrophages and dendritic cells are known as __ presenting cells.

antigen.

The adaptive immune system is characterized by its __ and memory.

specific response.

Neutrophils are the primary cell involved in __ inflammation.

acute.

Eosinophils are particularly involved in __ infections and allergic diseases.

parasitic.

Mast cells release components such as __ and heparin that protect against bacteria.

histamine.

The largest leukocyte, which differentiates into macrophages or dendritic cells, is called __.

monocyte.

T cells mature in the __ before entering circulation.

thymus.

B cells are activated by __ cells in the adaptive immune system.

T.

Type 1 hypersensitivity reactions are characterized by an immediate allergic response mediated by __ antibodies.

IgE.

Type 2 hypersensitivity reactions result in the antibody-mediated destruction of __.

cells.

Hypersensitivity Type 4 is mediated by __ cells.

T.

The function of antibodies includes neutralizing __ and agglutination of foreign cells.

bacteria/viruses.

The main types of antibodies include IgM, IgA, IgG, IgD, and __.

IgE.

Neutropenia, a condition of low neutrophil numbers, can occur after __.

chemotherapy.