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Fixed species-specific behaviours
Behaviours that are consistent within a species.
Brain's role
Critical for generating behaviour.
Phineas Gage (before injury)
Well-balanced mind, smart businessman, persistent.
Phineas Gage (after injury)
Fitful, irreverent, profane; 'no longer Gage.'
Significance of Phineas Gage case
Brain damage impacts personality and behaviour.
Neuron Doctrine
Neurons are discrete but function as a network.
Reticular Theory
Neurons form a continuous network.
Dendrites
Receive information.
Axon
Carries signals; covered by myelin sheath (formed by glial cells).
Nodes of Ranvier
Gaps in myelin that speed up signal transmission.
Soma (cell body)
Coordinates processes, contains the nucleus.
Grey Matter
Unmyelinated axons, cell bodies.
White Matter
Myelinated axons; signal 'jumps' for faster transmission.
Multiple Sclerosis (MS)
Myelin degradation → loss of neural signal → numbness, weakness, motor issues.
Sensory Neurons
Convert external stimuli to nervous signals (bipolar).
Motor Neurons
Control muscles; typically multipolar.
Interneurons
Modulate local activity (CNS, multipolar).
Purkinje Cells
Carry information from the cerebellum to brain/spinal cord.
Pyramidal Cells
Triangular cell body, found in the cerebral cortex.
Bipolar Cells
Sensory neurons in the retina.
Neurons
Transmit signals, action potentials, and neurotransmitters.
Glia
Support neurons, provide nutrients, and influence transmission.
Astrocytes
Manage blood-brain barrier, modulate activity.
Oligodendrocytes
Myelinate CNS neurons (up to 50 neurons).
Schwann Cells
Myelinate PNS neurons (1mm = 1000 cells).
Microglia
Brain's guardians; destroy pathogens, clean debris.
Resting Potential
-70mV; inside is negative relative to outside.
Action Potential
Electric spike (+40mV); follows 'all or none' principle.
Saltatory Conduction
Signal jumps between Nodes of Ranvier (faster).
Synapse
Gap where neurotransmitters transfer signals.
Acetylcholine (ACh)
Voluntary motor control, attention, memory.
Dopamine
Motor behaviour, pleasure; linked to schizophrenia (high) and Parkinson's (low).
Glutamate
Major excitatory transmitter.
GABA
Inhibitory; low GABA = seizures.
Serotonin
Mood, sleep, eating; low levels → depression.
Norepinephrine
Vigilance, awareness.
Endorphins
Pain relief, mood elevation.
Agonists
Increase neurotransmitter action (e.g., Amphetamine, Cocaine).
Antagonists
Decrease neurotransmitter function (e.g., Beta-blockers).
Key Mechanism of Drugs
Drugs alter receptor function but not action potential magnitude.
Epigenetics
Changes in gene expression without altering DNA methylation.
Influence of Epigenetics
Environment and experiences can turn genes 'on' or 'off.'
Genes
Units of heredity, made of DNA, organized in chromosomes.
Mutations
Cause diversity; subject to evolutionary pressures.
Heritability
Measure of how much variability in traits is due to genetics (0 to 1 scale).
Universal human behaviours
Behaviours like aversion to pain, socializing needs, and the drive to eat, reproduce, and seek understanding.
Human nervous system
An interacting network of neurons conveying electrochemical information throughout the body.
Central nervous system (CNS)
Consists of the brain and spinal cord.
Peripheral nervous system (PNS)
Comprises the somatic and autonomic nervous systems.
Sympathetic nervous system
Prepares the body for action in challenging situations.
Parasympathetic nervous system
Returns the body to a resting state.
Endocrine system
A network of glands producing and secreting hormones regulating functions like metabolism.
Pituitary gland
Known as the 'master gland' of the endocrine system.
Hypothalamus Role
Sends hormonal signals to the pituitary gland to regulate bodily functions.
Major divisions of the brain
Hindbrain, midbrain, and forebrain.
Function of hindbrain
Coordinates basic functions such as respiration, alertness, and motor skills.
Structure regulating heart rate
Medulla.
Function of cerebellum
Controls fine motor skills, balance, and coordination.
Function of midbrain
Orients organisms to sensory stimuli and is involved in movement and arousal.
Role of forebrain
Controls complex cognitive, emotional, sensory, and motor functions.
Subcortical structures
Thalamus, hypothalamus, hippocampus, amygdala, and basal ganglia.
Brain plasticity
The brain's ability to adapt to changes in sensory input and reassign functions.
Corpus callosum
A bundle of axons connecting the two hemispheres of the brain.
Structural vs. functional imaging
Structural imaging reveals brain anatomy; functional imaging shows brain activity.
MRI drawbacks
Slow, expensive, unsuitable for patients with metal implants.
fMRI
Detects blood flow changes in the brain, reflecting areas of neural activity.
Mirror neurons
Active when performing or observing an action, found in the frontal and parietal lobes.
Lateralization of language
Predominantly controlled by the left hemisphere, discovered by Broca and Wernicke.
Phineas Gage's case
Showed the frontal lobe's role in emotion regulation, planning, and decision-making.
PET scans drawbacks
Expose patients to radiation and are costly.
Hippocampus role
Creates new memories and integrates them into long-term storage.
Amygdala damage effect
Impairment in emotional processing, particularly fear.
Reflex arc
Neural pathway that controls reflex actions, often involving sensory, motor, and interneurons.
Transcranial magnetic stimulation (TMS)
Uses strong magnetic pulses to temporarily induce or block neuronal activity.
Somatosensory cortex
Located in the parietal lobe, it processes touch information from the body.