Endocrinology Exam 1

Function of Hypothalamus

produce hypophysiotropic hormones that control anterior pituitary gland, make hormones stored in posterior pituitary

Function of Ovaries

produce estrogen and progesterone, maintenance of pregnancy

Function of Pancreas

produce insulin and glucagon (regulate blood glucose)

Function of Parathyroid

produces parathyroid hormone (stimulates bone resorption, regulates blood calcium)

Function of Pineal Gland

produce melatonin

Function of Pituitary

hypophysis - produce tropic hormones that regulate other endocrine glands

Function of Testes

produce testosterone

Function of Thyroid

produce thyroxin (regulate metabolism, growth)

Function of Thymus

produce thymosin (stimulate T-cell development)

Melatonin Synthesis Rate Limiting Enzyme

N-acetyl Transferase (NAT)

tyrosine —> dopa Rate Limiting Enzyme

tyrosine hydroxylase

Catecholamines Synthesis Pathway

tyrosine —> dopa —> dopamine —> norepinephrine —> epinephrine

Acetyl CoA —> cholesterol Rate Limiting Enzyme

HMG CoA reductase

cholesterol —> pregnenolone Rate Limiting Enzyme

P450scc

pregnenolone —> progesterone Rate Limiting Enzyme

3B-HSD

corticosterone —> cortisol Rate Limiting Enzyme

P450cll

corticosterone —> aldosterone Rate Limiting Enzyme

P450aldo

testosterone —> dihydrotestosterone Rate Limiting Enzyme

5a reductase

testosterone —> estradiol Rate Limiting Enzyme

P450aro