PLASMA PROTEIN

What is the most abundant plasma protein?

Serum albumin, accounting for 55% of blood proteins.

What is the primary function of serum albumin?

To maintain oncotic pressure and transport lipids and steroid hormones.

What percentage of blood proteins do globulins make up?

38% of blood proteins.

What is the main function of fibrinogen?

Conversion to insoluble fibrin for blood clotting.

Which organ synthesizes most plasma proteins?

The liver.

What is the exception to liver-synthesized plasma proteins?

Immunoglobulins (antibodies).

What is the normal concentration range of albumin in plasma?

35-45 g/L.

What role do plasma proteins play in maintaining homeostasis?

They help maintain acid-base balance and distribute heat throughout the body.

Which plasma protein is important for iron transport?

Transferrin.

What are cytokines in plasma?

Proteins that regulate inflammation and blood cell formation.

What is the function of complement proteins in plasma?

To mediate immune and inflammatory responses to infectious agents.

What is the difference between plasma and serum?

Plasma contains fibrinogen and clotting factors, while serum does not.

Which plasma protein is reduced in neurological disorders?

Ceruloplasmin.

What plasma protein is significantly decreased in lung adenocarcinoma?

Gelsolin isoform 1 and complement factor H.

What is the function of haptoglobin in plasma?

To bind free hemoglobin and prevent its loss through the kidneys.

Which plasma protein is important for maintaining vascular integrity?

Alpha-2-macroglobulin.

What is the role of cystatin-C in plasma?

It acts as a cysteine protease inhibitor.

Which plasma protein is elevated in acute inflammation?

C-reactive protein (CRP).

What is the function of apolipoprotein A-I in plasma?

It is the major protein component of high-density lipoprotein (HDL) and helps in reverse cholesterol transport.

Which plasma protein is important for the innate immune response?

Complement C3.