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EKG
a recording of the electrical activity of the heart over a period of time
-allows clinicians to assess cardiac rhythm, conduction abnormalities, ischemia
Myocardial cells
-found in the muscular layers of the atria and ventricles
-contain myofibrils
Pacemaker cells
-found in the electrical conduction system responsible for generation of electrical impulses
-automaticity
Automaticity
ability of pacemaker cells to spontaneously generate their own electrical impulses
-specific to pacemaker cells
Excitability
The ability of cardiac cells to respond to electrical impulses
-characteristic shared by both cell groups
Conductivity
ability of cardiac cells to conduct the impulse to adjacent cardiac cells
both cell groups
Contractility
ability of cardiac cells to shorten and cause muscle contraction in response to electrical stimulation
-specific to myocardial cells
Electrolyte
A Charged impulse that helps generate electrical impulses in the heart
Sodium: primary ion outside cell, initiates depolarization by entering cells
Potassium: primary ion inside cell, regulated repolarization
Calcium: essential for contraction, triggers acti-myosin
Magnesium: stabilizes cardiac membranes and assists with regualtion
Depolarization
when a cardiac cell in stimulated by an electrical impulse, the membrane becomes permeable to ion exchange
-potassium begins to leave the cell, sodium enters
-muscle contraction follows depolarization
Repolarization
recovery from depolarization to polarized state
-cardiac cell cannot respond to stimuli until it has been repolarized
Cardiac Action Potential
Phase 0: depolarization
-sodium influx into cell
Phase 1: early repolarization
-sodium channels close and some potassium exits
Phase 2: Plateau
calcium moves into cell
potassium continues to leave cell
Phase 3: repolarization
-calcium channels close, potassium continues to move out
Phase 4: resting
-sodium-potassium pump actively moves sodium out and potassium in, restoring resting state
SA node
located in the upper right atrium near the inlet of the superior vena cava
-primary pacemaker of heart
-60-100 impulses per min
AV node
-located in lower right atrium
-relays electrfical impulse from atria to ventricles
-slows conduction to allow time for atria to contract
-secondary pacemaker (40-60 impulses per min)
-block rapid atrial impulses from being conducted into ventricles
Bundle branches and purkinje fibers
can serve as secondary pacemaker
firing rate 30-40 impulses per min
PR interval
the time from the onset of atrial depolarization to ventricular depolarization
PR segment
represents normal delay in the AV node
QT interval
total time for the ventricles to depolarize and repolarize
ST segment
represents ventricular repolarization
P wave
-normal P wave= SA node functioning properly
-represents atrial depolarization
-followed by atrial contraction
Duration: less than 0.12 seconds
P wave Abnormalities
Peaked: right atrial enlargement
Notched or wide: left atrial enlargement
Absent: Afib, SA node dysfunction
Inverted: impulse originated at AV node
Flutter: Aflutter
QRS complex
-second segment, normal menas normal ventricular conduction
-represents ventricular depolarization
-Pathological Q-wave represents old MI
Duration: 0.06-0.1 seconds
QRS complex abnormalities
wide: bundle branch block, Vtach, htperkalemia
Low voltage: pericardial effusion, obesity
Pathological Q: old MI
Delta wave: wolf-parkinson-white syndrome
Twave
ventricular repolarization
-reflects recovery phase
-0.1-.25 seconds
T wave abnormalities
Tall/peaked: hyperkalemia
Flat/flow: hypokalemia
Inverted: Ischemia, LVH, pericarditis
Biphasic: ischemia, repolarization abnormality
Cardiac Cycle
1 hearbeat (1 PQRST segment)
-represents sequence of systole and diastole
Isoelectric line
flat segment between cardiac cycles
Above isoelectric line: positive deflection
Bellow: negative deflection
Above and bellow: biphasic deflection
Waveform flow
Current towards positive pole: positive deflection
Current towards negative pole: negative deflection
Size of wave: depends on how much voltage is generated during depolarization
Refractory Period
time during cardiac cycle when a cell may or may not respond to an electrical stimulus
Absolute refractory period
period when cells cannot respond to an electrical stimulus, lasts from depolarization to most of repolarization
Relative refractory period
period during ventricular repolarization when repolarization is almost complete, and cells may respond to strong stimulus