Drugs for Parkinson's Disease

Amantadine

Used to help reduce tremors, stiffness, and movement problems in people with Parkinson’s disease.

What is the brand name for amantadine?

Symmetrel

What are the three dosage forms of amantadine?

Tablets, capsules, solution

What is the classification of amantadine?

Anticholinergics

Benztropine

Used to help reduce muscle stiffness and improve movement in people with Parkinson’s disease.

What is the brand name for benztropine?

Cogentin

What are the two dosage forms of benztropine?

Tablets, injection

What is the classification of benztropine?

Anticholinergics

Trihexyphenidyl

Used to reduce muscle stiffness and improve movement in people with Parkinson’s disease.

What is the brand name for trihexyphenidyl?

Artane

What are the two dosage forms of trihexyphenidyl?

Tablets, sustained-release capsules

What is the classification of trihexyphenidyl?

Anticholinergics

Carbidopa

Used to prevent levodopa from breaking down too early.

Levodopa

Used to create dopamine in the brain to improve movement symptoms.

What are the two brand names for the combination of carbidopa and levodopa?

Sinemet, Sinemet CR

What are the two dosage forms for the mix of carbidopa and levodopa?

Tablets, ER and CR tablets

Entacapone

Used to make levodopa last longer and reduce “wear-off” symptoms.

What is the brand name for the combination of carbidopa, levodopa, and entacapone?

Stalevo

What is the dosage form of the mix of carbidopa, levodopa, and entacapone?

Tablets

What is the classification of carbidopa?

Carbidopa/levodopa products

What is the classification of levodopa?

Carbidopa/levodopa products

What are the two possible classifications of entacapone?

Carbidopa/levodopa products & COMT inhibitors

Rasagiline

Used to help increase and maintain dopamine levels to improve movement symptoms.

What is the brand name for rasagiline?

Azilect

What is the dosage form of rasagiline?

Tablets

What is the classification of rasagiline?

MAO-B inhibitors

Selegiline

Used to prevent dopamine from breaking down.

Is selegiline used with levodopa?

Yes

Is it possible for selegiline to be used by itself?

Yes

Which is more common: for selegiline to be used by itself or with levodopa?

With levodopa

What are the three brand names for selegiline?

Eldepryl, Zelapar ODT, Emsam patch

What are the three dosage forms of selegiline?

Capsules, ODT, transdermal patch

What is the classification of selegiline?

MAO-B inhibitors

What is the brand name of entacapone by itself?

Comtan

Is entacapone ever prescribed by itself?

No

What dosage form is entacapone by itself sold as?

Tablets

Tolcapone

Used to help levodopa last longer and improve movement symptoms.

Is tolcapone used by itself or with levodopa?

With levodopa

What is the brand name for tolcapone?

Tasmar

What dosage form is tolcapone sold as?

Tablets

What is the classification of tolcapone?

COMT inhibitors

Apomorphine

Used to help solve sudden drop offs in another medication’s efficacy by acting like dopamine to restore movement.

What is the brand name for apomorphine?

Apokyn

What is the dosage form of apomorphine?

Subcutaneous injection

What is the classification of apomorphine?

Dopamine antagonists

Bromocriptine

Used to act like dopamine to improve movement symptoms.

What is the brand name for bromocriptine?

Parlodel

What are the two dosage forms of bromocriptine?

Tablets, capsules

What is the classification of bromocriptine?

Dopamine antagonists

Pramipexole

Used to act like dopamine to reduce stiffness, tremors, and slow movement.

What is the brand name of pramipexole?

Mirapex

What are the two dosage forms of pramipexole?

Tablets, ER tablets

What is the classification of pramipexole?

Dopamine antagonists

Ropinirole

Used to act like dopamine to reduce stiffness, tremors, and slow movement.

What is the brand name for ropinirole?

Requip

What are the two dosage forms of ropinirole?

Tablets, ER tablets

What is the classification of ropinirole?

Dopamine antagonists

Rotigotine

Used to act like dopamine to reduce stiffness, tremors, and slow movement.

What is the brand name of rotigotine?

Neupro

What is the dosage form of rotigotine?

Transdermal patch

What is the classification of rotigotine?

Dopamine antagonists