Protein Synthesis Inhibitors
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Last updated 10:19 PM on 3/29/26
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5 Terms
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Chloramphenicol
broad spectrum
binds 50S ribsomal subunit & inhibits peptide bond formation
side effects: bone marrow function
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Aminoglycosides
Streptomycin, neomycin, gentamycin
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Aminoglycoside
broad spectrum
changes shape of 30S ribosomal unit & prevents formation of initation complex
4
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Tetracycline
from Streptomyces spp.
broadest spectrum antibiotic - interferes with tRNA attachment
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Macrolides
Erythromycin - binds 50S subunit, preventing translocation
alternative to penicillin
effective against (+)
