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In the pyruvate DH complex, which of the following serves the function of being reduced by lipoamide?
flavin adenine dinucleotide (FAD)
which of the following statements about the generation of ATP in the electron transport chains in correct?
The F1 subunit of the ATP synthase contains the catalytic center than synthesizes ATP
True of False. Pyruvate can be converted into either acetyl-CoA or lactate
true
Which of the following reactions above are involved in shuttling reducing equivalents into the mitochondrion?
malate—>oxaloacetate
Dinitrophenol (DNP) is a drug that disrupts the hydrogen ion gradient produced in the electron transport chain and uncouple ETC from oxidative phosphorylation. Which of the following will result from use of DNP?
anaerobic metabolism will increase
for the reaction shown below which of the following is correct?
isocitrate + NAD+ —> alpha-ketoglutarate + CO2 + NADH
isocitrate is oxidized to alpha ketoglutarate
the energy used to drive the production of ATP during oxidative phosphorylation comes from…
a proton gradient generated during the electron transport chain
true or false. In complex V or ATP synthase, the cyclic motion of the gamma subunit is responsible for modifying the conformation of the interface between the alpha and beta subunits, forming 3 distinct conformation of the active site.
true
which enzyme of the citric acid cycle catalyzes a substrate-level phosphorylation?
succinyl-CoA synthetase
as a result of glycolysis, pyruvate oxidation and the citric acid cycle, only a small portion of the energy of glucose has been converted to ATP. At this point, the majority of the usable energy is contained in:
reduced electron carriers NADH and FADH2
B vitamins enhance energy because…
they are required for the coenzymes involved in both the pyruvate dehydrogenase complex and an enzyme in the citric acid cycle
the most important control step for the citric acid cycle is…
the pyruvate dehydrogenase complex (PDH complex)
the electron transport chain…
facilitates orientation of a variety of redox centers allowing spontaneous flow of electrons
which complex accepts electrons from NADH?
complex I
what is the purpose of coenzyme Q?
it is a 1 and 2 electron gateway that controls flow of electron to complex III