Bone Pathology Lecture Notes by Dr. Janelle Diaz

A collection of flashcards summarizing key terms and concepts in bone pathology, focusing on various conditions that affect bones in the maxillofacial region.

Osteogenesis Imperfecta

A heterogeneous group of heritable disorders characterized by osteopenia and bone fragility, known as Brittle Bone Disease.

Types of Osteogenesis Imperfecta

Classified as types I through IX, based on inheritance patterns and clinical features among other factors.

Clinical Manifestations of Osteogenesis Imperfecta

Include severity that varies by type, blue sclerae, and fractures occurring often depending on the age.

Idiopathic Osteosclerosis

Focally increased bone density of unknown cause, not attributable to inflammatory, dysplastic, neoplastic, or systemic disorders.

Paget Disease of Bone

A metabolic bone disorder characterized by abnormal resorption and deposition of bone, causing skeletal distortion and weakening.

Central Giant Cell Granuloma

An intraosseous lesion of unknown etiology, controversial as a reactive process vs benign neoplasm.

Simple Bone Cyst

An empty or fluid-containing bone cavity, often asymptomatic and with a predilection for the metaphysis of long bones.

Differential Diagnosis in Paget Disease of Bone

Includes comparison with cemento-osseous dysplasia due to similar radiographic signs.

Treatment Options for Osteogenesis Imperfecta

Include physiotherapy, orthopedic surgery, pain management, and various emerging therapies like gene therapy.

Radiographic Signs of Osteogenesis Imperfecta

Include osteopenia, bowing deformity of the long bones, and increased number of Wormian bones in the skull.