Hormone Therapy (HRT) for Transgender Patients

These flashcards cover key concepts and details from the lecture on hormone therapy for transgender patients, assisting students in their exam preparation.

What are the objectives of the hormone therapy session?

To assess hormone therapy readiness, discuss risks & benefits, review medications, visit timelines, and necessary lab work.

What is one key aspect of hormone therapy readiness?

Background sharing about the transgender journey.

What type of mental health support should a patient have before starting HRT?

A counselor, psychiatrist, or therapist.

What is one of the goals of HRT therapy for transgender patients?

To help the patient achieve gender-affirming goals.

List one benefit of feminizing hormones for Male to Female patients.

Breast development.

What is a permanent change due to feminizing hormones?

Change in body shape (increased fat on hips).

What is a risk associated with feminizing hormone therapy?

Blood clots.

Who should NOT take estrogen?

Anyone with a history of estrogen-dependent cancer.

What is spironolactone used for in feminizing hormone therapy?

It decreases endogenous testosterone.

How often should baseline blood work be done for patients starting HRT?

At least initially, and then periodically as per the treatment protocol.

What are two potential emotional side effects of feminizing hormone therapy?

Emotional changes and increased risk of depression.

What is one contraindication for taking testosterone?

Pregnancy.

What is a benefit of masculinizing hormones for Female to Male patients?

Larger clitoris.

What are two medications used in masculinizing hormone therapy?

Testosterone and Finasteride.

What is a major risk of testosterone therapy in FTM patients?

Increased risk of heart disease.

How long should a patient typically be on HRT before considering surgical options?

At least 6 months.

What is the typical starting dose for Estradiol in feminizing therapy?

2-6 mg daily.

What is the role of counseling in hormone therapy readiness?

To provide support and assess the patient's ability to consent.

What lab work is recommended at the initial visit for HRT?

CMP (Comprehensive Metabolic Panel) and possibly an A1C and lipid panel.

What is a reversible effect of testosterone therapy?

Skin oiliness.

What potential effect could be irreversible for someone undergoing masculinizing hormone therapy?

Deepened voice.

What is one key consideration during follow-up visits post-HRT?

Assessing hormone tolerance and adjusting doses accordingly.

What is the maximum dose for spironolactone in feminizing hormone therapy?

400 mg daily.

What is the purpose of the HRT consent form?

To ensure understanding of risks and benefits of therapy.

What condition relates specifically to the use of testosterone with caution?

Uncontrolled coronary artery disease.

What is one side effect of spironolactone?

Risk of hyperkalemia.

What type of hormone therapy requires baseline and periodic blood work?

Both masculinizing and feminizing hormone therapy.

What is a possible allergic consideration for testosterone cypionate?

Allergy to sesame oil.

What is an important aspect of treatment goals for transgender patients?

To avoid targeting specific hormone levels but staying within desired ranges.

What dietary factor should be discussed prior to starting HRT?

Fertility and contraception.

How often should total testosterone levels be monitored during masculinizing therapy?

Every 3 months for the first year, then every 6 to 12 months thereafter.

What might be a concern for those who have a family history of estrogen-dependent cancer before starting HRT?

Increased risk of breast cancer.

What does the review checklist for hormone readiness include?

Medical history, fertility plans, mental health, and understanding of HRT's permanency.

What is one reason transgender patients may experience mood changes during HRT?

Hormonal fluctuations.

What should be discussed along with hormone therapy regarding sexual health?

Fertility implications.

What is an important part of decision-making for patients considering HRT?

Engaging in shared decision-making about risks and benefits.

What is a reversible physical effect commonly associated with feminizing hormone therapy?

Skin softening.

In masculinizing hormone therapy, what effect signifies permanent change?

Cessation of menstrual period.

What is an essential follow-up item after starting masculinizing therapy?

Regular monitoring of CBC and testosterone levels.

What is one side effect related to the use of testosterone therapy?

Acne and scarring.