Biology 213W - 11-20-24 | Quizlet

Epitope

the part of an antigen molecule to which an antibody attaches itself

T cells have...

T cell receptors on their surface

B cells make...

antibodies (immunoglobins) both bound to their surface as receptors and also secreted as effector molecules

Specificity if binding between epitope of antigen and antigen binding site of antibody

size
shape
charge distribution

Recombination

deletes DNA between randomly selected V segment and J segment and makes the antigen receptors unique

CD4 is a marker for

T h cells

CD8 is a marker for

T c cells

Humoral response

secretes antibodies that defend against extracellular pathogens

Cell mediated response

defend against infected cells, cancer and transplant tissues

T helper cell

when active it clones itself and activates cytotoxic T cells and B cells using cytokines

Cytokines are...

signaling molecules

Macrophage

Large white blood cell that removes bacteria, foreign particles, and dead cells

A plasma cell is...

an activated B cell that secretes antibodies

Perforin

pore-forming protein

Polyclonal response

multiple B cells activates for each infection

Naaturally adquired

infection (A)
antibodies pass down (P)

Artificially adquired

vaccines (A)
immune serum (P)

Mast cells

Cells that release chemicals (such as histamine) that promote inflammation