Antimicrobial selection in food animal medicine

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38 Terms

1

What is the first step in the antimicrobial decision-making process?

Is an antibiotic necessary

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2

When deciding if you want to use an antibiotic you want to compare the potential clinical benefit verses what?

  1. Treatment costs

  2. Potential for violative residues

  3. Potential for adverse drug events

  4. Selection for AMR

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3

What can we use to determine the legality of an antimicrobial?

AMDUCA

Prohibited

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4

How can we determine the efficacy of an antibiotic?

Drug spectrum

AST

Clinical experience

Drug label

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5

How can we determine the safety of an antibacterial?

Patient safety

Administrator safety

Food produce safety (residues)

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6

How can we determine the owner compliance of an antibiotic?

Dosing regimen (route and frequency)

Cost

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7

T/F florcon is a fluoroquinolone and is not allowed for extra label use in large animals?

False

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8

W

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9

What is danofloxacin labeled for?

BRD

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10

What is mikotil?

Tilmicosin

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11

What is mikotil (tilmicosin) labeled for?

BRD associated with Manheimia haemolyitca, Pasteurella multocida, Histophilus somni

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12

Why would we not want to use Micotil (Tilmicosin)?

It has a 45 day withdrawal time

Dairy cattle

Can hurt human

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13

What is sustain III?

Sulfamethazine

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14

Why would we not use Sustain III (sulfamethazine) for BRD?

Dairy calves older than 20 months old

You have to oral bolus each calf

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15

What is polyflex?

Ampicillin

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16

Why would we not use polyflex (ampicillin) for BRD?

Mycoplasma is a likely pathogen and it does not cover it

Requires multiday dosage

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17

What is NuFlor?

Florfenicol

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18

Why would we not use florfenicol for a BRD case?

Expensive

Hard to pull up

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19

What is excede?

CFA Ceftiofur

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20

Why would we not use CFA ceftiofur for a BRD case?

Requires injection at base of the ear

Does not cover mycoplasma

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21

What is Bio Mycin?

Oxytetracycline

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22

Why would we not use BioMycin for a BRD case?

Resistance

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23

How do you dose danofloxacin?

Single or multi

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24

How do you dose Ceftiofur CFA?

Single

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25

How do you dose sulfamethazine?

Single

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26

How do you dose florfenicol?

Single or multi

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27

How do you dose oxytetracycline?

Single or multi

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28

How do you dose tilmicosin?

Single

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29

How do you dose ampicillin?

Multi

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30

What can injection of tilmicosin (micotil) do in humans?

Can be fatal to humans. Do not use if workers are poorly trained

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31

What are some precautions of danofloxacin?

CNS stimulation

Cartilage damage in young animals

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32

What are some safety concerns of micotil (tilmicosin) in attle?

Anaphylaxis, swelling

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33

What are the primary BRD pathogens?

Mannheimia haemolytica

Pasteurella multocida

HIstophilus somni (gram negative anaerobe)

Mycoplasma bovis

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34

What drugs can be used for the control of BRD?

Exceed

Danofloxacin

Florphenicol

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35

What drugs have a short withdrawal time and can treat BRD?

Danofloxacin

Ampicillin

Sulfas can be ok (12 days)

Ceftiofur can be ok (13 days)

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36

What drugs can be used in lactating dairy cattle with BRD?

Ceftiofur

Ampicillin

Oxytetracycline

Florfenicol (extra label but can be used technically) (long withdraw time)

Tilmicosin (long milk withdrawal time)

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37

At what age are you no longer allowed to use sulfas in dairy cattle?

Older than 20 months

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38

What is the milk withdrawal time for ceftiofur?

None

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