Donor History Questionnaire Deferrals

MLS 4130 (Last updated Nov. 2025)

Taking an antibiotic or other medication for infection

Until end of medication regimen

Pregnancy

6 weeks after end

Taken a medication on the Medication Deferral List

Depends on medication, see MDL

Took aspirin in the last 48 hours

None, but donation cannot be used for platelets

Donated blood, platelets, or plasma in the past 8 weeks

Until 8 weeks since last donation OR 16 weeks since last apheresis

Received a live-attenuated or bacterial vaccination in the past 8 weeks

14 days after vaccination date

Received a killed, synthetic, mRNA, influenza, or toxoid vaccination in the past 8 weeks

None if asymptomatic

Received a smallpox vaccination in the past 8 weeks

21 days after vaccination, until scab has fallen off naturally, OR 56 days after vaccination & 14 days after symptom resolution

Was in contact with someone who received a smallpox vaccination in the past 8 weeks

None if asymptomatic, 14 days after symptom resolution

Taken a medication by mouth to prevent HIV infection in the past 3 months

3 months after end of medication regimen

Had non-anal sexual contact with one or more new partner(s) in the past 3 months

None

Had anal sexual contact with one or more new partner(s) in the past 3 months

3 months after last encounter

Had sexual contact with anyone who has ever had a positive test for HIV infection in the past 3 months

Encouraged not to donate if symptomatic of HIV infection

Received money, drugs, or other payment for sex in the past 3 months

3 months after last encounter

In the past 3 months, had sexual contact with anyone who has, in the past 3 months, received money, drugs, or other payment for sex

3 months after last encounter

Used needles to inject drugs, steroids, or anything not prescribed by a doctor in the past 3 months

3 months since last encounter

In the past 3 months, had sexual contact with anyone who has used needles, in the past 3 months, to inject drugs, steroids, or anything not prescribed by their doctor

3 months since last encounter

Had syphilis or gonnorhea or been treated for it in the past 3 months

3 months after end of regimen

Had sexual contact with a person who has hepatitis in the past 3 months

3 months after last encounter

Lived with a person who has hepatitis in the past 3 months

3 months after last contact

Had an accidental needle stick in the past 3 months

3 months after last exposure

Got a tattoo in the past 3 months

None unless not from a state-regulated facility

Had an ear or body piercing in the past 3 months

3 months unless via single-use equipment

Received a blood transfusion in the past 3 months

3 months since procedure (unless autologous)

Received a transplant in the past 3 months

3 months since procedure (unless autologous)

Recevied a graft in the past 3 months

3 months since procedure (unless autologous)

Donated a double unit of red blood cells using apheresis in the past 16 weeks

16 weeks after last donation

Been in juvenile detention, lockup, jail, or prison for more than 72 hours consecutively in the past 12 months

12 months after last incarceration date

Received any medication by injection to prevent HIV infection

2 years after end of regimen

Been to a non-malaria-endemic country in the past 3 years

None

Been to a malaria-endemic country in the past 3 years

3 months after departure

Had a continuous stay of >5 years in a malaria-endemic country

3 years after departure

Ever had a positive test for HIV infection

Permanent

Ever taken any medication to treat HIV infection

Permanent

Ever had malaria

3 years after symptom resolution

Ever received a dura mater graft or xenotransplantation product

Indefnite (unless autologous)

Ever had any sort of cancer, including leukemia

Depends on donation center

Ever had any problem with heart or lungs

6 months after any cardiac events, procedures, or diagnoses

Ever had a clotting factor disorder/deficiency that requires treatment

Indefinite unless XII

Ever had von Willebrand disease

Indefnite unless mild

Ever had a positive test for Babesia

2 years after positive result with non-reactice test