Chapter 1.1-1.10 PTCB CPhT

What is the generic name for Lipitor?

Atorvastatin (cholesterol-lowering statin)

Therapeutically equivalent drugs must be:

Bioequivalent and pharmaceutically equivalent

The FDA resource for checking therapeutic equivalence is called the:

Orange Book

Which combinations can cause life-threatening interactions?

Warfarin + NSAIDs, Simvastatin + Grapefruit, MAOIs + Tyramine

A patient with asthma should not take:

Atenolol

Which of the following is NOT a route of administration?

Dialysis

A suspension should be:

Shaken before use

A side effect of diphenhydramine (Benadryl) is:

C. Drowsiness

Anaphylaxis is considered a

Allergy

What is lisinopril used to treat?

High blood pressure

Calcium supplements are commonly used to treat or prevent

Osteoporosis

Insulin should be stored:

In the fridge until opened

Reconstituted oral antibiotics usually last:

7–14 days

Which of the following is a narrow therapeutic index (NTI) drug?

Warfarin

Why are NTI drugs dangerous?

Small changes in dose can be toxic

What happens if calcium and phosphate are mixed improperly?

They form crystals

Which of the following affects drug compatibility?

pH

Light
Container material

What is the recommended temperature range for refrigerated drugs?

36–46°F

Which of the following should be stored in a light-resistant container?

Nitroglycerin

Which medications are NTI drugs?

Warfarin, Lithium, Digoxin

Which medication is most likely to cause bleeding if combined with aspirin?

Warfarin

A pharmacy technician should avoid shaking which medication?

Insulin

Which abbreviation means "by mouth"?

PO

Drugs with a narrow therapeutic index require close

Monitoring

Which vitamin is needed for blood clotting and interacts with warfarin?

Vitamin K

What’s the proper way to store vaccines?

Between 2–8°C

Which med is a biguanide?

Metformin

Which med is a common supplement for cholesterol?

Fish oil

What is the purpose of the Orange Book?

To identify therapeutic equivalents

What is the brand name for omeprazole?

Prilosec

Which class does furosemide belong to?

Diuretic

The term “AB-rated” in the Orange Book means:

Bioequivalent and safe substitute

Two drugs with the same active ingredient and strength are always therapeutically equivalent.

False

Which supplements can interact with prescription medications?

Vitamin K, St. John’s Wort

Grapefruit juice can increase the effects of:

Simvastatin

Which dosage form is designed for extended release?

ER capsule

A medication applied to the skin for local effect is called a:

Topical

Which of the following is a serious adverse effect of clozapine?

Agranulocytosis

Common side effects of opioids include:

Constipation, Respiratory depression, Drowsiness

Levothyroxine is indicated for:

Hypothyroidism

Albuterol is used to relieve

Bronchospasm (or asthma attacks)

A reconstituted antibiotic should be:

Refrigerated and used within 14 days

Which of the following must be protected from light?

Nitroglycerin

Which NTI drug is used to prevent seizures?

Phenytoin

Why are NTI drugs dangerous if not dosed precisely?

Small dosage changes can be toxic

What happens when incompatible drugs are mixed?

They may precipitate or degrade

Select all that apply: Physical incompatibilities may occur when:

Mixing acidic/basic drugs, Storing too long, Wrong container

Which of the following drugs is an ACE inhibitor?

Lisinopril

A controlled substance must be:

Kept in a locked cabinet

A technician should avoid substituting NTI drugs unless:

The pharmacist approves

The route “subQ” means:

Under the skin

Which drug is classified as an antidiabetic?

Glipizide

Controlled room temperature is:

68–77°F

Which drug interaction can cause excessive bleeding?

Warfarin + NSAIDs

The medication that treats GERD and reduces stomach acid is:

Omeprazole