Clinical Microbiology 1: Growth-dependent and growth-independent methods of Pathogen Identification

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10 Terms

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Bacteremia

Bacteria in blood

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Minimum Inhibitory Concentration (MIC)

Using tube dilution assay to see the sensitivity to antibiotics

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E-test

MIC is read from the edge of the clear zone using the scale on the strips.

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Antigen

Puzzle piece that is connected to antibody

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Epitope

Small regions of large molecules that are recognizable

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Serotype

Strain of a species

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Serology

Use of antigen-antibody reactions to detect

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Direct immunoassays

Measure the amount of antigen, antigen is sandwiched between antibodies

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Indirect immunoassays

Detect antibodies by using pateint antibody that binds to lab antibody and antigen.

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qPCR

measures the amount of dsDNA with flouresence.