Cardiac Physiology and Pressure-Volume Loops

Flashcards for cardiac physiology based on pressure-volume loops.

Pressure Volume Loop: A to B

Isovolumetric contraction

Pressure Volume Loop: B to C

Ejection

Pressure Volume Loop: C to D

Isovolumetric relaxation

Pressure Volume Loop: D to A

Ventricular filling

End-Systolic Pressure-Volume Relationship (ESPVR)

Represented by the slope of the C point (end systole); indicates contractility.

Acute Heart Failure Impact on ESPVR

Results in a reduced end-systolic pressure-volume relationship (ESPVR)

End-Diastolic Pressure-Volume Relationship (EDPVR)

Measure of ventricular compliance that changes with diastolic function. Changes with compliance, generally with restrictive myopathies.

Stroke Volume Representation on Pressure-Volume Loop

Represented by the diameter of the loop.

Afterload Representation on Pressure-Volume Loop

Represented by the height of the curve.

Contractility

Represented by the end-systolic pressure-volume relationship.