UT CYTO 601

voided urine main points

holistic sample, low cellularity

bladder wash main points

cystoscope, limited sample

ureter/renal pelvis brushing/washing main points

can have false positive

cath urine main points

UTI risk, papillary group artifact

ileal conduit/loop urine main points

GI cells, melamed-wolinska bodies

seeing renal tubular cells suggests?

kidney disease

seminal vesicle cells

bizarre w/smudgy chromatin, golden brown lipofuscin pigment

CMV tends to infect what cells?

renal tubular

which species of schistosoma inc SCCa risk?

haematobium, terminal spine

copora amylacea is commonly seen with what cells?

benign prostatic glandular

malakoplakia is associated with what bodies?

michaelis-gutmann, calcified w/bull’s eye appearance

michaelis-gutmann bodies stain pos for?

PAS, Fe, Ca

Polyomavirus features

homogenous glassy nuclear inclusions, or netlike chromatin

degenerative urothelial cell features

bizarre, pyknotic, margination, fading, fragmentation, smudgy

stone atypia/calculi features

tight groups of atypical looking urothelial cells

LGUN features

papillary groups w/fibrovascular core

HGUC features

SINGLES, high NC, pleomorphic, irreg, hyperchrom, coarse, nucleoli

transitional cell papilloma features

BENIGN, papillary groups w/scant fibrovascular core

UT AdCa originates where?

dome of bladder

mets epithelial tumors

SCCa, AdCa, NEC

mets non-epithelial tumors

sarcoma, hematologic, melanoma

direct extension to bladder

AdCa of prostate/colorectum, SCCa of cervix

mets tumors to bladder

renal cell carcinoma, breast, GI

Uro Vysion positivity criteria

more than 1 pair of signals, or no signals from gold

Uro Vysion red signal

chromosome 3

Uro Vysion green signal

chromosome 7

Uro Vysion aqua signal

chromosome 17

Uro Vysion gold signal

LSI 9p21

likely clin hx for polyomavirus infection?

renal tx

umbrella cells are most often seen in what specimen type?

instrumented

S haematobium inc risk for what type of SCCa?

bilharzial