AZ Bioscience Domain 4

sequence

the order of bases in a nucleic acid segment

BLAST (basic local alignment search tool)

an online software that compares a nucleotide or protein sequence to a database and determines the statistical significance

homologous

a gene sequence that has the same origin or function as another

DNA subway

a genome database to compare sequences and work with phylogenetic relationships

MEGA (molecular evolutionary genetics analysis)

a tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web-based databases, estimating rates of molecular evolution, and testing

flybase

a database for drosophila genetics and molecular

biology

genom.org

a peer-reviewed genome sciences journal

NCBI

the National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information

copy number variant

the number of copies of a gene that varies

from one individual to another

inversion

a segment of DNA that is reversed end to end

SNP (single nucleotide polymorphism)

a difference of one nucleotide between homologous sequences

translocation

a segment of DNA that is inserted into a nonhomologous chromosome

E-value

the expected number of hits to see by chance when searching a sequence database, the E-Value decreases exponentially as the Score (S) of the match increases

RCSB PDB (protein database)

Database of the 3Ds hapes of proteins, nucleic acids, and complex molecules

control

a predetermined consistency throughout an experiment

dependent variable

the factor of an experiment that is altered as a result of the independent variable

hypothesis

a testable concept based upon factual information

independent variable

the factor of an experiment that is

mindfully varied throughout an experiment

variable

a factor in an experiment that is either purposely changed or altered as a result of another variable

column/bar graph

a visual model of data comparing categories

on a like topic with bars

pie/circle graph

a visual model of data comparing the percentage of categories on a like topic

scatter/line graph

a visual model of the relationship of 2 or more variables

gray literature

professional literature that has not been peer

reviewed

peer reviewed

when information is confirmed as accurate by a person of equal educational knowledge

white paper

information printed from a credible institute such as a government agency

abstract

a summary of the crucial factors of a paper

literature review

a secondary source that summarizes current knowledge on a topic

model organism

a species utilized in research due to characteristics (short life span, easy to culture, short generation time)

cell line

a culture that has a uniform genetic makeup due to it being generated from a single cell

propagate

to culture or grow up a sample of an organism

ethics

behavior governed by moral principles that takes into

account all stakeholders

bioethics

the ethics surrounding biological research

genetically modified organisms (GMO)

an organism whose has been given a gene from another organism

stakeholders

a person, organization, or business that has a particular interest in a situation

risk management

the evaluation of a situation to assess the potential hazards

quality control

testing of a product continually to ensure it fits

the expectations

quality assurrance

maintaining the quality of a product by examining the manufacturing process over extended amounts of time

trend analysis

long term evaluation of data to identify trends