Cancer Signaling Pathways
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Last updated 11:35 PM on 1/21/26
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4 Terms
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EGFR
activation triggers downstream MAPK and PI3K pathways that promote survival and proliferation
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HER2
amplification causes ligand-independent signaling and aggressive tumor behavior
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VEGF
stimulates angiogenesis, enabling tumors to establish their blood supply
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RAS mutations
lock the MAPK pathway in an active state, regardless of receptor input
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