Drugs for ADHD and Narcolepsy Classification

Function

CNS stimulants: elevate mood, produce a sense of increased energy and alertness, decrease appetite, enhance performance

Mechanism of action and drug effects

CNS effects:

• Mood elevation or euphoria

• Increased mental alertness and capacity for work

• Decreased fatigue and drowsiness

• Prolonged wakefulness

Respiratory effects:

• Relaxation of bronchial smooth muscle

• Increased respiration

• Dilation of pulmonary arteries

Indications

• ADHD

• Narcolepsy

• Obesity

Contraindications

• Known drug allergy

• Cardiac structural abnormalities

• Recent MAOI usage

Adverse effects

• Wide range; dose related

• Tend to “speed up” body systems

• Common adverse effects include:

  • Palpitations, tachycardia, hypertension, angina, dysrhythmias, nervousness, restlessness, anxiety, insomnia, nausea, vomiting, diarrhea, dry mouth, increased urinary frequency, other

•  increase HR and BP, angina, anxiety, insomnia, headache, tremor, blurred vision, increase metabolic rate, GI distress, dry mouth, psychiatric disorders

• Common w/ atomoxetine: headache, abdominal pain, vomiting, anorexia, and cough

Interactions

Vary from class to class