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SURFACE AREA TO VOLUME RATIO (3.3.1)
SURFACE AREA TO VOLUME RATIO (3.3.1)
Why can very small organisms simply change substances across their surface
Because there is a big exchange surface but also a smaller distance from the outside of the organism to the middle of it
Why do smaller mammals need a high metabolic rate
Due to their high surface area to volume ratio they will lose heat quickly therefore a higher metabolic rate provides the energy required to maintain stable conditions
Why can larger mammals have a slower metabolic rate
Because they have a lower surface area to volume ratio therefore they lose heat more slowly
What are some examples of adaptations to increase surface area to volume ratio
Villi and micro villi - Absorbtion of digested food
Alveoili and bronchioles - Gas exchange
Spiracles and tracheoles - Gas exchange
Gill filaments and lamellar - Gas exchange
GAS EXCHANGE (3.2.2)
GAS EXCHANGE (3.2.2)
What is the formula for calculating rate of diffusion using FICK’S law
Rate of diffusion = (surface area x difference in concentration) / length of diffusion path
What is ventilation (breathing) controlled by
The diaphragm and the antagonistic interaction between the external and internal intercostal muscles
What is pulmonary ventilation
Pulmonary ventilation is the total volume of air that is moved into the lungs during one minute (dm3 min-1)
What is the formula for pulmonary ventilation
Pulmonary ventilation = tidal volume x ventilation rate
Why are alveoli epithelial cells very thin and surrounded by capillaries
To minimise diffusion distance and maintain a concentration gradient
What is the special adaptation that fish have to breathe called
Countercurrent flow to maintain the concentration gradient to enable diffusion to occur
How many layers of gills are there on both side of the head in a fish
4
What are gills made up of
Stacks of Gill filmanets which are covered in lamellae positioned at right angled to the filament
What does this help to achieve
A higher surface area so that when fish open their mouth water rushes in and over the gills and then out through a hole in their head
How does countercurrent exchange work
Water flows over the gills in the opposite direction to the flow of blood in the capillaries
What does counter current flow ensure
That equilibrium is not reached and that the diffusion gradient is maintained across the entire length of the Gill lamellae
How do insects respire
They have Spiracles which are little openings along the abdomen which lead to the trachea
What does the trachea branch off into
Tracheoles which help to deliver the oxygen to all respiring cells
Give 3 adaptations of tracheoles for efficient gas exchange
Thin walls for short diffusion distance (one cell thick)
Highly branched for shorter diffusion distance
Highly branched to provide large surface area for gas exchange
What is the main method of gas exchange at rest in insects
Diffusion
What method of gas exchange Is used during periods of high activity
Mass transport can occur
How does mass transport occur
The abdominal muscles contract and relax which actively moves air in and out of the tracheal system, helping to maintain the gradient for oxygen and carbon dioxide
What product is made when the insect is very active and respires anaerobically
Lactate
What effect does the production of lactate have on respiration
Lactate lowers the water potential in muscle cells which causes water at the ends of the tracheoles to move into the muscle cells via osmosis
Why is less fluid and more air in the tracheoles beneficial for respiration
Gases diffuse more quickly through air than through liquid
What two adaptations do Spiracles have to limit water loss
They can open and close to reduce water loss
They have hairs on them to trap humid air and reduce the water potential gradient, reducing evaopration
What is an insects exoskeleton made from and what property does it have
Chitin and impermeable
Why do stomata close at night
To reduce water loss by evaporation
What are xerophytic plants
Plants adapted to survive in environments with limited water
Name two adaptations to the leaves of xerohytes that helps retain water
Curled leaves trap moisture which increases local humidity
Thicker cuticles to reduce evaporation
3.3.3 DIGESTION AND ABSORPTION
3.3.3 DIGESTION AND ABSORPTION
Which two enzymes do carbohydrates require to hyrdolyse them into monosaccharides
Amylases
Membrane bound disaccharidases
Where is amylase produced and what does hydrolyses starch into
The pancreas
The salivary glands
Hydrolyses it into maltose
Why does the pancreas release more amylase into the top part of the stomach (the duodenum)
Because the enzyme amylase is denatured by the strong stomach acid
What is the name of the membrane bound disaccharidases that are bound to the membrane of the ileum cells
Sucrase - digests sucrose into its monosaccharides
Lactase - digests lactose into its monosaccharides
What is the word equation for maltose hydrolysis
Maltose + water —→ A Glucose + A Glucose
What is the word equation for sucrose hydrolysis
Sucrose + Water —→ Glucose + Fructose
What is the word equation for lactose hydrolysis
Lactose + Water —→ Glucose + Galactose
Where does protein digestion begin, continue into and finish
The stomach and continues into the duodenum and finishes in the ileum
Name the 3 enzymes that are required to digest proteins
Endopeptidases
Exopeptidases
Membrane bound dipeptidases
What do endopeptidases do
Hydrolyses the peptide bonds between amino acids in the middle of the polymer chain
What do Exopeptidases do
Hydrolyses peptide bonds between amino acids at the end of the polymer chain
What do the membrane bound dipeptidases do
Hydrolyses peptide bonds between two amino acids
Why do the endopeptidases come first
So that they break the large polypeptide chain into smaller ones to increase the surface area for Exopeptidases to work
What is the name of the enzyme that digest lipids
Lipase
What other thing are required to digest lipids (non enzyme)
Bile lats
Where is lipase produced and what does it do to lipids
In the pancreas and it can hydrolyse the ester bond in triglycerides to form monoglycerides and fatty acids
(one glycerol molecule and 3 fatty acids)
Where are bile salt produced, where are they released from and what do they do
Liver
Gallbladder
Emulsify lipids to form lipid droplets called micelles
(This increases the surface area for lipase to act on)
Do bile salts digest the lipids chemically or physically
Physically because no chemical bonds are broken
Is lipase digestion chemical or physical
Chemical because the ester bonds in the triglycerides are broken
In mammals, what cells are the products of digestion absorbed via
Ileum cells
What is the ileum wall covered in
Villi
What do ileum epithelial cells have on their membranes
Micro villi to further increase the surface area
In what 3 ways do these features maximise absorption
Increased surface area
Decreasing diffusion distance
Maintain strong concentration gradient
What are micelles
Water soluble vesicles formed by
fatty acids
glycerol
monoglycerides
bile salts
What do the bile salts do to the fatty acids and micelles
Makes them water soluble
What two ways to micelles help in lipid absorption
They make the fatty acids more soluble in water, allowing them to stay suspended in watery contents of small intestine
They carry and release fatty acids to epithelial lining of ileum, close to the cells surface.
Why is it important that the micelles carry the fatty acids close to the ileum cells
Maintains a high concentration gradient of fatty acids near the epithelial cells which allows them to be absorbed into the epithelial cells via simple diffusion
Where are the fatty acids reformed into triglycerides inside the cell and where are they sent to for transportation to lymphatic system
In the golgi apparatus where they are packaged into vesicles to be sent to the cell surface membrane where they are then transported to the lymphatic system
How are Glucose and amino acids absorbed into the epithelial cells
Co transport
3.3.4 MASS TRANSPORT
3.3.4 MASS TRANSPORT
What structure does haemoglobin have
A quaternary structure
Where is oxygen loaded
In regions of high partial pressure of oxygen (e.g alveoli)
Where is oxygen unloaded
Regions of low partial pressure (e.g respiring tissues)
What is oxyhaemoglobin dissociation show on
The oxyhaemoglobin dissociation curve
How many molecules of oxygen can haemoglobin associate with
4
What does oxygen affinity mean
Oxygen affinity refers to the strength with which haemoglobin (Hb) binds to oxygen, indicating how easily it picks up oxygen in the lungs and releases it in the tissues
What is name of the effect that allows haemoglobin's ability to bind with oxygen to change with carbon dioxide (CO2) levels and pH, allowing for efficient oxygen delivery
The Bohr effect
What is the Bohr effect
Carbon dioxide dissolves in liquid
Carbonic acid forms and decreases pH
This changes the shape of the haemoglobin slightly
Affinity for oxygen decreases in respiring tissues
Haemoglobin delivers the oxygen to the site of respiring cells so that aerobic respiration can continue
What does myoglobin do
Has a very high affinity to oxygen, even at very low partial pressures so acts as an oxygen store
What type of circulatory system do mammals have
A closed, double circulatory system
Why is it referred to as being closed
Because the blood remains within the vessels
Why is it referred to as a double circulatory system
The blood passes through the heart twice in each circuit
One circuit delivers blood to lungs and the other delivers blood to the rest of the body
Why do the aorta and venca cava both branch off
They have one branch going to the brain and body (aorta) and one branch going from the body and brain (pulmonary circuit) to the heart
Venca cava divided into superior (from brain to heart) and inferior (from body to heart)
Aorta branches with one branch going to the body and one branch going to the brain
Why do mammals require a double circulatory system
To manage the pressure of the bloodflow
Why does the blood pass through the lungs at a lower pressure
Prevents damage to the capillaries in the alveoli and also reduces blood speed, enabling more time for gas exchange
In contrast, why do we want the blood leaving the lungs to be pumped out at a high pressure
So that the blood reaches all the respiring cells in the body
Name the blood vessels attached to the kidneys
Renal artery
Renal vein
Name the blood vessels attached to the lungs
Pulmonary artery
Pulmonary vein
Name the blood vessels attached to the heart
Vena cava
Aorta
Pulmonary artery
Pulmonary vein
Coronary arteries
What do arteries do
Carry blood away from heart and into arterioles
What do arterioles do
Smaller than arteries and connect to the capillaries
What do capillaries do
Connect the arterioles to the veins
What do veins do
Carry deoxygenated blood back into the heart (have valves)
What does the aortic tissue do when the ventricles contract/relax
Contracts = stretch
Relax = Recoil
What does this help to achieve
Smooth outflow of blood and consistent pressure
What does the thick SMOOTH muscular wall and smooth endothelium (inside wall) help with
Prevents bursting due to the high pressure
Reduces friction
Why do arterioles have a Thicker layer of muscle than arteries
So tat they can vasonctrict (reduce size of lumen) and vasoldilate (increase size of lumen) to regulate the floor of blood to capillaries
Why do veins have a wide lumen and valves
Rescue bloodflow resistance
Prevent backflow of blood
How many red blood cells can fit though a capillary at once and what effect does this have on the flow of blood
One at a time which slows it down - more time for gas exchange
Why are capillaries made of flattened endothelial cells
Reduces the diffusion distance
What is tissue fluid
Fluid containing water, glucose, amino acids, fatty acids, ions and oxygen which bathes the tissues that has been forced out of the capillaries
Why do capillaries have small gaps in the walls
So that liquid and small molecules can be forced out
As blood enters the capillaries from the arterioles, what does the smaller diameter result in
A high hydrostatic pressure so water, glucose, amino acids, fatty acids, ions and oxygen are forced out
What is this process known as
Ultrafiltration
What remains in the capillary
Large proteins
Red blood cells
Platelets
What do the large molecules that remain in the capillaries do
A lowered water potential
Why is the hydrostatic pressure lowered towards the venue end of the capillaries
Loss of liquid
Why is not all of the liquid that went into the tissue fluid reabsorbed
Because osmosis means that once equilibrium is reached, no more liquid can be absorbed