PACOP. Pcol (green 156-300)

Where can you find kernicterus as its side effect?

sulfonamide

Drug of choice for typhoid fever:

chloramphenicol

Drug of choice for pseudomembranous colitis:

vancomycin

drug of choice for herpes zoster (shingles) infection:

acyclovir

Drug of choice for trichomoniasis:

metronidazole

This anti-infective agent has disulfiram-like effect when taken with alcoholic beverages:

metronidazole

This drug can be used for both PTB and leprosy:

rifampicin

Vitamin given to prevent pernicious anemia:

cobalamine

Antiviral agent also used for leukemia:

vidarabine

Vitamin which has an antisterility effect:

vitamin E

Mechanism of action of aminoglycosides:

inhibit protein synthesis

Mechanism of action of sulfonamides:

prevent PABA to form folic acid

Mechanism of action of penicillin:

inhibit the synthesis of bacterial cell wall

Mechanism of action of erythromycin:

inhibit protein synthesis

Mechanism of action of nystatin:

inhibit ergosterol

Mechanism of action of isoniazid:

inhibit mycolic acid

Niclosamide:

anthelimintic agent

Quinine:

antimalarial agent

A patient is being treated for nighttime sedation. Which alteration in warfarin dosage is indicated?

a decrease because its metabolism has been inhibited

Displacement of a drug from plasma binding sites would usually be expected to:

increase tissue levels of the drug

Widely used in cancer management that are classified as steroid hormone:

BOTH

the ff. are the effects of morphine:

pin-point pupils

Long-acting anti-diabetic agents:

BOTH

The ff. are antidotes for morphine poisoning:

both a and b

The ff. are non-narcotic analgesics:

ALL

Type of epilepsy which involves the spread of electrical firing in a single hemisphere of the brain:

partial

Richest source of vitamin A:

fish liver oil

Which of the following effect/s of histamines are mediated through H2 receptors, EXCEPT:

release of catecholamines from adrenal medulla

Drug used to treat amoebiasis can be categorized as the following, EXCEPT:

peripheral

An antiviral drug used for parkinsonism which releases dopamine from storage vesicles:

amantidine

Drug of choice for mania:

lithium carbonate

Vitamin K deficiency state:

hemorrhage

Type of general seizure which involves the abnormal movement of muscles:

myoclonic seizures

________ is effective in the management of gastric acid hypersecretion and symptoms relief with Zollinger- Ellison syndrome:

omeprazole

Oral hypoglycemic drugs, EXCEPT:

ultralente insulin

Isoniazid may produce peripheral neuropathy and can be prevented by co-administration of:

BOTH

Oral hypoglycemic drugs, EXCEPT:

ultralente insulin

Isoniazid may produce peripheral neuropathy and can be prevented by co-administration of:

BOTH

Most potent member of the general anesthetics:

methoxyflurane

A Phenobarbital derivative which is used in combination therapy for types of epilepsy:

primidone

Precursor of Vitamin D3:

cholesterol

Responsible for calcification of bone and renal phosphate clearance:

cholecalciferol

Not to be administered to neonates:

sulfonamide

The H2 histamine receptor lockers are of great value in treating patients with:

Zollinger-Ellison syndrome\`

Thyroid function is controlled by the tropic hormone _______:

thyrotropin-stimulating hormone

A painful sensation associated with complex biochemical mechanisms:inflammation

inflammation

Which of the following penicillin/s is/are penicillinase-resistant?

oxacillin

Agent that facilitates the expulsion of gases from the GIT:

anti-flatulents

First line drug against all common intestinal nematodes:

mebendazole

The ff. are effects of morphine:

ALL

It inhibits the DNA-dependent RNA polymerase of Mycobacteria:

rifampicin

Therapy choice for diarrhea:

Oral rehydration salts

Xanthine alkaloid used as bronchodilator:

theophylline

Slow-acting antimalarial agents:

pyrimethamine

The ff. are general anesthetics:

ALL

For the treatment of postoperative retention of urine that the patient is likely to e benefited with drug/s possessing which of the ff. property(ies):

smooth muscle stimulant property

The ff. are antipsychotic drugs:

ALL

Inhibition of carbonic anhydrase enzyme may be therapeutically useful for which of the ff. purposes, EXCEPT:

to counter the effects of vasopressin on the kidney

Androgens can cause fluid retention, leading to:

edema

Drug of choice for status epilepticus in children:

Phenobarbital

The ff. drugs are systemic anti-fungals, EXCEPT:

clotrimazole

Which of the following are the main advantages of ranitidine over cimetidine?

ALL

Among the following, which is the primary action of heparin responsible for its anticoagulant effect?

activation of plasma antithrombin III

The following are uricosuric agents:

both a and b

The ff. effect/s of histamine is/are mediated through H1 receptors, EXCEPT:

increased gastric secretion

The following are non-narcotic analgesics:

ALL

Which of the following drug/s primarily act on the proximal tubule (site 1) to produce its/ their diuretic effect, EXCEPT:

furosemide

Also known as absence seizures:

petit malAgents that facilitate the easy removal of compacted fecal matter:

Agents that facilitate the easy removal of compacted fecal matter:

cathartics

Vitamin B12 deficiency state:

pernicious anemia

The non-systemic antacids are preferred because of the safety as well as:

longer duration of action

Bactericidal drugs that are applied to non-living material:

disinfectants

An anti-inflammatory drug also used for malaria:

chloroquine

This heart condition develops when the blood volume is great compared to the space available inside blood vessels; this can be caused by edema:

hypertension

An anti-psychotic drug possessing antihistaminic and anti-emetic properties:

promethazine

Which of the ff. tends to cause black, tarry stools?

ferrous sulfate

Fecal softener:

docusate

Both oxytocin and vasopressin increase:

uterine contractility

carbonic anhydrase inhibitor:

acetazolamide

Anti-TB drug which causes optic neuritis:

ethambutol

An antidote for heparin overdosage:

protamine sulfate

Potassium ion- hydrogen ion ATPase dependent pump inhibitor:

omeprazole

A non-selective beta antagonist, it blocks both beta 1 and beta 2 receptors:

propranolol

Each of the following drugs produces a reflex increase in sympathetic activity and tachycardia as side effects, EXCEPT:

clonidine

Which of the following drugs could be used effectively to alleviate postpartum breast engorgement in patients who are breastfeeding their infants?

oxytocin

Angina is treated with:

BOTH

Agents that facilitate the easy removal of compacted fecal matter from the large intestines:

laxatives

Megaloblastic anemia can develop as consequence of prolonged therapy with each of the following, EXCEPT:

ethosuximide

Type of anemia which produces immature RBC decreasing their oxygen carrying capacity (this results due to the decreased biosynthesis of thymidylate which in turn is utilized in the synthesis of DNA):

megaloblastic

The side effects of steroids diminish when the drug is given via:

inhalation

inhalation

cyanocobalamine

In a person with ulcerative colitis and diarrhea, which agent would have the greatest potential for producing perforation of the intestine?

morphine

Anti-diarrheal agents include all of the ff., EXCEPT:

magnesium hydroxide

Administration of each of the following drugs during chronic dicumarol therapy may cause an increase in the anticoagulant effect of dicumarol:

Phenobarbital

The richest source of vitamin K:

green leafy vegetables

A stimulant laxative also used as an indicator in acid-base titrations:

phenolphthalein

The most specific drug therapy for neostigmine-induced diarrhea would be:

tincture of belladonna

Antidote for INH toxicity:

pyridoxine

Anti-ulcer drug which possesses both anti-secretory and cytoprotective properties:

misoprostol

Antidote for carbon monoxide poisoning:

all of the above