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world anti doping association (WADA) prohibited list
may include substance and methods that satisfy any two of the following 3 criteria:
has potential to enhance or does enhance sport performance
represents an actual or potential health risk to athlete
violates spirit of sport (outlined in code)
substances/methods which mask effect or detection of prohibited substances are also prohibited
substance that has not been approved for human use is prohibited as well
WADA prohibited list
reviewed annually in consultation with scientific, medial, and anti-doping experts
ensures it reflects current med and scientific evidence and doping practices
comes into effect January 1st and published 3 months prior
exceptional circumstances allows anything to be added to list at anytime
masters athletes
aging typically = decrease in lean muscle mass
typically older than 35
train and involved in athletic competition for older adults
many are experienced athletes
age depends on sport
25 swimming
30 track and field
35 weight lifting
40 long distance running
50 senior game
international masters games association (IMGA)
founded in 1995
Recognized by IOC
Organizes:
⢠World Masters Games
⢠Winter World Masters Games
⢠European Masters Games
⢠Pan-American Masters Games
⢠Asia-Pacific Masters Games
masters athletes brackets
Masters-Level Athletics Participants compete in 5-year age brackets
35-39; 40-44; 45-49; 50-54; 55-59; etc
masters athlete challenge
many seniors on prescription meds:
⢠5.7% of seniors prescribed 5 or more drug classes
⢠26.5% of seniors prescribed 10 or more drug classes
⢠8.4% of seniors prescribed 15 or more drug classes
most meds are not banned substances, but some have ingredients that are
hormone replacement therapy (HRT)
Estrogen (help menopause)
Testosterone (help andropause)
human growth hormone (HGH)
controversial (harms vs benefits)
estrogen with menopause
Less estrogen
Menstrual cycle ceases
estrogen combats:
Vaginal dryness
⢠Night sweats
⢠Hot flashes
⢠Insomnia
⢠Difficulty concentrating
testosterone
Declines with age (serum testosterone)
Changes in:
⢠Lean muscle mass
⢠Muscle strength
⢠Physical function
⢠Exercise performanceh

human growth hormone
Exercise stimulates GH
⢠Response to that GH decreases over time
⢠Secreted by the pituitary
⢠Stimulates liver and other tissues to make IGF-1:
⢠Promotes bone growth
⢠Promotes muscle growth
⢠Reduces body fat (lipolytic)
⢠Detriments: cardiac instability, hypertension, insulin resistance

anabolic steriods
Derivatives of testosterone
Enhance athletic performance:
⢠Strength gains of 5-20%
⢠Increase lean body mass 2-5kg
Needed for asthma and rheumatologic conditions
serious side effects of anabolic steriods
Unhealthy cholesterol profile (increase overall, decrease HDL); Heart Attack (from BP and atherosclerosis); stroke; blood clots; liver failure; hepatic neoplasms; ligament/tendon injury; hairloss, acne
⢠Male specific: atrophy of the testes, decreased sperm production, erectile dysfunction, gynecomastia, prostate issues
⢠Female specific: inhibition of ovulation, irregular menstrual cycle, lower voice, facial hair, breast atrophy
Psychological side effects: aggression; confusion; disordered sleep; anxiety; paranoia; hallucinations
Athletes should be counselled on prevention
analgesics and anti inflammatories
Wanting to compete āPain Freeā; pain is very common after 50
Narcotic Analgesics (opioids)
Non-Steroidal Anti-Inflammatories (NSAIDS)
narcotic analgesics (opioids)
Euphoria; false feeling of invincibility
⢠Increase pain threshold ā may ignore early warning of injury (more damage)
⢠Physical and psychological dependence
Adverse effects: drowsiness, mental fog, nausea, vomiting,
dizziness, constipation, trouble with urination
High doses: respiratory depression, apnea, circulatory
depression, hypotension (low BP), muscle rigidity, coma, shock,
cardiac arrest.
non steroidal anti inflammatory (NSAIDs)
⢠Useful for mild to moderate pain and inflammation
⢠Commonly used for DJD and OA
⢠Available OTC
⢠Complications/toxicity: GI bleeding, dyspepsia, peptic ulcer disease, acute renal failure (due to renal vasoconstriction), worsening of hypertension, and congestive heart failure
NSAIDs and COX-2 Inhibitors

hypertension medications
Common in general population
Often not as big a problem for endurance athletes (exercise keeps BP down)
execise and sport participation in athletes with hypertension

recommendations on exercise restrictions

diuretics
Less desirable in distance athletes ā dehydration
⢠Effective way to lower HBP
⢠Misuse ā forces weightloss (used for making weightclass)
⢠Can lead to muscle cramps
angiotensin converting enzymes inhibitor (ACE)
High blood pressure medication
⢠No negative effect on training or competition
⢠Sanctioned by WADA
calcium channel blockers
Well tolerated for physically active patients
⢠Effective blood pressure medication
⢠Should not impact performance
beat blockers
Decreases BP
⢠Can inhibit Glycogenolysis (causing hypoglycemia post intense
exercise)
⢠Anti-tremor effects ā banned in high accuracy sports
⢠Archery, shooting, diving, ice skating
eryhthropoietin
āāBlood Dopingā
⢠Increase oxygen carrying capacity
⢠Popular for endurance athletes
⢠Increased risk of MI or stroke
dietary supplementation and ergogenic aid
changing needs that occur with age
changing needs that occur with exercise
presence of chronic illness or disease
level of competition
consequently supplements may:
intentionally contain prohibited substances
unintentionally be contaminated with prohibited (eg. contaminated source ingredients erroneous source ingredients, cross contamination during manufacturing)
be mislabeled
in addition supplements may:
not accurately list the ingredients (eg. falsify, omit)
not accurately list relative amount of each ingredient per dose
make false certification claims (eg. WADA approved)
not list important cautionary info (health side effects)
alcohol
Inhibits Antidiuretic Hormone (ADH) and is therefore a diuretic
Post exercise exacerbates fluid loss
May limit glycogen replenishment
⢠So fatigue and dehydration may occur during subsequent exercise bout
Increased blood pressure, and heart rate
cannabis
Under review
Little is known
Possibly pain relief?
On WADA prohibited list since 1984 (still there for THC)
CBD (non psychoactive) no longer prohibited since 2018
caffeine
Most frequently used drug in the world
CNS stimulation
Enhanced muscular force (strength and endurance), concentration, energy levels, less reported fatigue, enhanced alertness
No negative performance effects
Increased time to exhaustion
For doses exceeding 200mg
Removed from WADA Prohibited list in 2007
Can lead to insomnia, increase BP, HR
creatine
Taken to ābulk upā muscle mass
Increase strength and mass, explosive power
Decrease fatigue
Not banned, may impact renal health
energy metabolism

production of energy in body

glucosamine
to minimize degeneration
retain hyalin cartilage
summary
drug use and abuse is major problem facing sport today
taking performance enhancing drugs or doping has long history in sport
elderly athlete has certain elevated nutritional needs compared to younger athletes
estrogen in women may prevent osteoporosis, maintain physical vitality, treat postmenopausal symptoms, and reduce depression- certain HRT rugs are banned
high doses of testosterone, esp when combined with strength training, increase fat free mass, muscle size, and strength in men
performance enhancing drugs can have deleterious effect on prostate
anabolic steroids can cause an unhealthy cholesterol profile, heart attack, stroke, liver failure, and type 2 diabetes
HGH can cause hypertension, pedal edema, carpel tunnel syndrome, and prediabetic condition
older athletes do not respond to creatine supplementation to the same extent as young athletes