Test 2 MOA MCQ | Quizlet

What is the primary mechanism of action of Digoxin

A. Beta-adrenergic agonist

B. Sodium channel blocker

C. Na⁺/K⁺-ATPase inhibitor

D. ACE inhibitor

C

Dobutamine exerts its effect mainly by stimulating:

A. Alpha-1 receptors

B. Beta-1 adrenergic receptors

C. Dopamine receptors

D. Muscarinic receptors

B

Dopamine primarily acts on which receptor at low doses?

A. Alpha-1

B. Beta-2

C. Dopaminergic D1

D. Muscarinic M3

C

Pimobendan is a

A. Beta-blocker

B. ACE inhibitor

C. Phosphodiesterase III inhibitor and calcium sensitizer

D. Calcium channel blocker

C

Pimobendan is a

A. Beta-blocker

B. ACE inhibitor

C. Phosphodiesterase III inhibitor and calcium sensitizer

D. Calcium channel blocker

C

Reserpine lowers blood pressure by:

A. Inhibiting ACE

B. Blocking alpha-1 receptors

C. Depleting catecholamines from nerve endings

D. Increasing dopamine levels

C

Prazosin works by:

A. Blocking beta receptors

B. Blocking alpha-1 adrenergic receptors

C. Inhibiting angiotensin II receptors

D. Activating dopamine receptors

B

Hydralazine affect blood pressure by:

A. Increasing sodium excretion

B. Blocking calcium channels

C. Directly relaxing arteriolar smooth muscle

D. Stimulating baroreceptors

C

Isoxsuprine acts as a:

A. Diuretic

B. Uterine stimulant

C. Beta-adrenergic agonist with vasodilator effect

D. Alpha-2 agonist

C

Pentoxifylline improves blood flow by:

A. Blocking alpha receptors

B. Inhibiting platelet aggregation and increasing RBC flexibility

C. Inhibiting prostaglandins

D. Decreasing heart rate

B

Propranolol is classified as a:

A. Selective beta-1 blocker

B. Non-selective beta-blocker

C. Calcium channel blocker

D. Alpha-2 agonist

B

Metoprolol is a:

A. Non-selective beta-blocker

B. Selective beta-1 blocker

C. Alpha-1 blocker

D. Dopamine agonist

B

Furosemide acts on the kidney by:

A. Blocking sodium channels in distal tubule

B. Inhibiting carbonic anhydrase

C. Inhibiting Na⁺/K⁺/2Cl⁻ symporter in loop of Henle

D. Inhibiting aldosterone receptors

C

Chlorothiazide is a:

A. Loop diuretic

B. Potassium-sparing diuretic

C. Thiazide diuretic

D. Osmotic diuretic

C

Mannitol is an example of a(n):

A. Thiazide diuretic

B. Loop diuretic

C. Osmotic diuretic

C

Acetazolamide works by:

A. Inhibiting aldosterone

B. Blocking carbonic anhydrase in proximal tubule

C. Inhibiting Na⁺/Cl⁻ transport

D. Increasing potassium retention

B

Spironolactone is a:

A. Loop diuretic

B. Aldosterone antagonist

C. Thiazide diuretic

D. Sodium channel blocker

B

Amlodipine lowers blood pressure by:

A. Beta-1 blockade

B. ACE inhibition

C. Calcium channel blockade

D. Alpha-1 stimulation

C

Verapamil is a:

A. Beta-blocker

B. Calcium channel blocker

C. Loop diuretic

D. ACE inhibitor

B (class IV)

Benazepril acts as an:

A. Alpha-2 agonist

B. ACE inhibitor

C. ARB

D. Beta-blocker

B

Captopril belongs to which class?

A. Angiotensin II receptor blockers (ARBs)

B. Calcium channel blockers

C. ACE inhibitors

D. Beta-blockers

C

Telmisartan is classified as a:

A. ACE inhibitor

B. Calcium channel blocker

C. Angiotensin II receptor blocker (ARB)

D. Aldosterone antagonist

C

Quinidine is used as a(n):

A. Antihypertensive

B. Class I antiarrhythmic (Na⁺ channel blocker)

C. Calcium channel blocker

D. Diuretic

B

Apomorphine is primarily used as a:

A. Diuretic

B. Dopamine antagonist

C. Emetic (dopamine agonist in CRTZ)

D. Sedative

C

Xylazine is an:

A. Alpha-2 adrenergic agonist with sedative and emetic effects

B. Beta-blocker

C. Muscarinic antagonist

D. Dopamine agonist

A

Metoclopramide acts by:

A. Stimulating alpha-2 receptors

B. Blocking dopamine (D2) receptors and enhancing GI motility

C. Blocking calcium channels

D. Inhibiting carbonic anhydrase

B

What is the mechanism of action of Ondansetron

C

Diphenhydramine acts primarily as a:

A. H2 receptor antagonist

B. H1 histamine receptor antagonist (antihistamine)

C. Serotonin antagonist

D. Beta-blocker

B

Aprepitant is classified as a:

A. Cannabinoid receptor agonist

B. NK1 receptor antagonist

C. H1 blocker

D. Dopamine antagonist

B

Dronabinol exerts antiemetic effects by:

A. Inhibiting serotonin reuptake

B. Blocking NK1 receptors

C. Acting as a cannabinoid receptor agonist

D. Anticholinergic action

C

Lactulose reduces ammonia in hepatic encephalopathy by:

A. Enhancing dopamine signaling

B. Acidifying colonic contents

C. Blocking H2 receptors

D. Stimulating opioid receptors

B

Loperamide exerts its antidiarrheal effect by:

A. Blocking calcium channels

B. Stimulating motilin receptors

C. Activating peripheral opioid receptors

D. Inhibiting serotonin

C

Aluminum hydroxide acts as a(n):

A. Proton pump inhibitor

B. Antacid (neutralizes gastric acid)

C. Antihistamine

D. Anti-inflammatory

B

Cimetidine is a:

A. H1 receptor blocker

B. H2 histamine receptor antagonist

C. Proton pump inhibitor

D. NSAID

B

Omeprazole inhibits acid secretion by:

A. Blocking H2 receptors

B. Inhibiting the gastric H⁺/K⁺ ATPase pump

C. Stimulating prostaglandin release

D. Blocking muscarinic receptors

B

Misoprostol protects the gastric mucosa by:

A. Blocking dopamine receptors

B. Stimulating prostaglandin E1 receptors

C. Blocking H2 receptors

D. Inhibiting serotonin

B

Pirenzepine reduces gastric acid secretion by:

A. Blocking muscarinic M1 receptors

B. Stimulating opioid receptors

C. Inhibiting NK1 receptors

D. Activating dopamine receptors

A

Diazepam acts as a:

A. Serotonin antagonist

B. GABA-A receptor agonist (benzodiazepine)

C. Opioid agonist

D. NMDA antagonist

B

Metoclopramide promotes gastric motility by:

A. Blocking NK1 receptors

B. Blocking dopamine D2 receptors

C. Stimulating alpha-1 receptors

D. Blocking calcium channels

B

Cisapride enhances GI motility via:

A. Dopamine blockade

B. Muscarinic stimulation

C. Serotonin 5-HT4 receptor agonism

D. Beta-adrenergic stimulation

C

Ranitidine is a:

A. Proton pump inhibitor

B. H2 histamine receptor antagonist

C. Muscarinic antagonist

D. Antacid

B

Erythromycin increases GI motility by:

A. Acting as a dopamine antagonist

B. Stimulating motilin receptors

C. Blocking 5-HT3 receptors

D. Inhibiting H2 receptors

B

Bethanechol stimulates GI and bladder motility by:

A. Blocking dopamine receptors

B. Inhibiting acetylcholine breakdown

C. Acting as a muscarinic receptor agonist

D. Blocking calcium channels

C

Lidocaine acts as a:

A. Sodium channel blocker (local anesthetic and antiarrhythmic)

B. Calcium channel blocker

C. Beta-blocker

D. Dopamine agonist

A

Cortisone exerts anti-inflammatory effects by:

A. Blocking COX-2

B. Inhibiting cytokine production via glucocorticoid receptors

C. Antihistamine activity

D. Mast cell stabilization

B

Captopril acts by:

A. Blocking angiotensin II receptors

B. Blocking ACE (angiotensin-converting enzyme)

C. Blocking beta-1 receptors

D. Increasing aldosterone release

B

Benazepril is best classified as a:

A. ARB (angiotensin receptor blocker)

B. Calcium channel blocker

C. ACE inhibitor

D. Beta-1 antagonist

C

Telmisartan lowers blood pressure by:

A. Blocking alpha-1 receptors

B. Blocking angiotensin II AT1 receptors (ARB)

C. Inhibiting sodium transport

D. Beta-2 agonism

B

Butorphanol is a:

A. Full mu-opioid receptor agonist

B. Mixed opioid agonist-antagonist

C. Pure kappa antagonist

D. Serotonin reuptake inhibitor

B

Codeine is classified as a:

A. NSAID

B. Full mu-opioid receptor agonist

C. Partial opioid agonist

D. Anticholinergic

C

N-acetyl-L-cysteine acts by:

A. Blocking prostaglandins

B. Binding heavy metals

C. Replenishing glutathione stores

D. Blocking dopamine receptors

C